Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 5/20 | 0.35 |
| ▸ | NPY1R | P25929 | 3/20 | 0.35 |
| ▸ | OTC | P00480 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3203673 | 0.84 | NOS1 (0.38) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396391 | 0.84 | NOS1 (0.34) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL27681071 | 0.83 | NOS1 (0.37) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396344 | 0.81 | CA12 (0.36) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL8414057 | 0.80 | NPY4R (0.38) | NPY4RNPY1ROTCDPP7NPY2R | |
| SCHEMBL11897923 | 0.80 | NPY4R (0.38) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396394 | 0.80 | CA12 (0.36) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396449 | 0.80 | CA12 (0.36) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL7776928 | 0.80 | NOS1 (0.37) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL9237239 | 0.80 | NPY4R (0.39) | NOS1NOS3NOS2NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220347212-A1 | PROPHYLACTIC AND THERAPEUTIC USE OF MITOCHONDRIA AND COMBINED MITOCHONDRIAL AGENTS | CHILDREN'S MEDICAL CENTER CORPORATION | 2022-11-03 | — | — | US | disclosed |
| EP-3962365-A1 | PROPHYLACTIC AND THERAPEUTIC USE OF MITOCHONDRIA AND COMBINED MITOCHONDRIAL AGENTS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-03-09 | — | — | EP | disclosed |
| WO-2020222866-A1 | PROPHYLACTIC AND THERAPEUTIC USE OF MITOCHONDRIA AND COMBINED MITOCHONDRIAL AGENTS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-11-05 | — | — | WO | disclosed |
| EP-1058725-B1 | USE OF BACTERIA ENDOWED WITH ARGININE DEIMINASE TO INDUCE APOPTOSIS AND/OR REDUCE AN INFLAMMATORY REACTION AND PHARMACEUTICAL OR DIETETIC COMPOSITIONS CONTAINING SUCH BACTERIA | ACTIAL FARMACEUTICA LDA (PT) | 2008-04-09 | — | — | EP | disclosed |
| US-7147847-B2 | Use of bacteria endowed with arginine deiminase to induce apoptosis and/or reduce an inflammatory reaction and pharmaceutical or dietetic compositions containing such bacteria | VSL PHARMACEUTICALS, INC. (US) | 2006-12-12 | — | — | US | disclosed |
| US-20030215429-A1 | Use of bacteria endowed with arginine deiminase to induce apoptosis and/or reduce an inflammatory reaction and pharmaceutical or dietetic compositions containing such bacteria | MENDES S.R.L. (IT) | 2003-11-20 | — | — | US | disclosed |
| US-6572854-B1 | Lactobacillus brevis | MENDES S.R.L. (IT) | 2003-06-03 | — | — | US | disclosed |