Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | NPY4R | P50391 | 5/20 | 0.35 |
| ▸ | NPY1R | P25929 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3203673 | 0.96 | NOS1 (0.38) | NOS1NOS3NOS2DPP8DPP9 | |
| SCHEMBL27681071 | 0.94 | NOS1 (0.37) | NOS1NOS3NOS2DPP8DPP9 | |
| SCHEMBL6130812 | 0.80 | DPP7 (0.40) | DPP8DPP7NPY4RNPY1RALOX15 | |
| SCHEMBL941102 | 0.80 | NPY4R (0.44) | NOS1NOS3NOS2DPP7NPY4R | |
| SCHEMBL4094683 | 0.80 | NPY4R (0.44) | NOS1NOS3NOS2DPP7NPY4R | |
| SCHEMBL6917505 | 0.80 | DPP7 (0.40) | DPP8DPP7NPY4RNPY1RALOX15 | |
| SCHEMBL4598754 | 0.80 | NOS1 (0.37) | NOS1NOS3NOS2DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL940707 | 0.79 | NPY4R (0.43) | NOS1NOS3NOS2DPP7NPY4R | |
| SCHEMBL13396344 | 0.79 | CA12 (0.36) | NOS1NOS3NOS2DPP8DPP9 | |
| SCHEMBL13396391 | 0.79 | NOS1 (0.34) | NOS1NOS3NOS2DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140854-A2 | METHODS FOR THE SYNTHESIS OF ALPHA-HYDROXY-BETA-AMINO ACID AND AMIDE DERIVATIVES | CORVAS INTERNATIONAL, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035868-A2 | METHODS FOR THE SYNTHESIS OF ALPHA-HYDROXY-BETA-AMINO ACID AND AMIDE DERIVATIVES | CORVAS INTERNATIONAL, INC. (US) | 2000-06-22 | — | — | WO | disclosed |