⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118105 | 0.93 | — | — | |
| SCHEMBL8788415 | 0.84 | PLAU (0.31) | — | |
| SCHEMBL12493459 | 0.84 | — | — | |
| SCHEMBL8786674 | 0.78 | — | — | |
| SCHEMBL8787739 | 0.73 | G6PD (0.33) | — | |
| SCHEMBL4806239 | 0.72 | TSHR (0.32) | — | |
| SCHEMBL8788974 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL5318359 | 0.70 | — | — | |
| SCHEMBL11895018 | 0.68 | — | — | |
| SCHEMBL4019693 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032532-A1 | \"PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF\ | SYMED LABS LIMITED (IN) | 2012-03-15 | — | — | WO | claimed |
| WO-2011055188-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF ILOPERIDONE | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2011-05-12 | — | — | WO | claimed |
| WO-2012164516-A1 | PROCESS FOR THE PREPARATION OF ILOPERIDONE | LUPIN LIMITED (IN) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012153341-A1 | A PROCESS FOR THE PREPARATION OF ILOPERIDONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | ARCH PHARMALABS LIMITED (IN) | 2012-11-15 | — | — | WO | disclosed |
| WO-2012063269-A2 | PROCESS FOR PREPARING ILOPERIDONE | CADILA HEALTHCARE LIMITED (IN) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012032532-A1 | \"PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF\ | SYMED LABS LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011055188-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF ILOPERIDONE | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |
| EP-0730452-A4 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST ROUSSEL PHARMA (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0730452-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST MARION ROUSSEL, Inc. (US) | 1996-09-11 | — | — | EP | disclosed |