Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829587 | 0.84 | BACE1 (0.53) | RIPK1TMEM97SIGMAR1PIK3C3BACE1 | |
| SCHEMBL7599925 | 0.82 | CCNC (0.40) | TMEM97SIGMAR1BACE1SCD5 | |
| SCHEMBL6246105 | 0.78 | RIPK1 (0.66) | RIPK1TMEM97SIGMAR1SCD5PDE5A | |
| SCHEMBL4293223 | 0.77 | PIK3C3 (0.45) | RIPK1PIK3C3NTRK1NTRK3NTRK2 | |
| SCHEMBL27364822 | 0.75 | BACE1 (0.53) | RIPK1TMEM97SIGMAR1PIK3C3BACE1 | |
| SCHEMBL18783107 | 0.75 | RIPK1 (0.44) | RIPK1PIK3C3NTRK1NTRK3NTRK2 | |
| SCHEMBL29116156 | 0.75 | RIPK1 (0.49) | RIPK1NTRK1SCD5MAOBPDE5A | |
| SCHEMBL14829293 | 0.74 | BACE1 (0.42) | RIPK1TMEM97SIGMAR1BACE1SCD5 | |
| SCHEMBL14829504 | 0.74 | BACE1 (0.42) | RIPK1TMEM97SIGMAR1BACE1SCD5 | |
| SCHEMBL29138895 | 0.74 | CCNC (0.45) | HDAC1HDAC8HDAC6SCD5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910320-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-04-16 | — | — | EP | claimed |
| WO-2007011065-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-25 | — | — | WO | claimed |