Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.49 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401264 | 0.84 | RIPK1 (0.49) | RIPK1TACR1MAOA | |
| SCHEMBL29116144 | 0.82 | RIPK1 (0.54) | RIPK1PDE5AJAK2NTRK1MAOB | |
| SCHEMBL27077230 | 0.81 | RIPK1 (0.49) | RIPK1SCD5NPC1PDE5ADRD4 | |
| SCHEMBL6246105 | 0.80 | RIPK1 (0.66) | RIPK1SCD5PARP10PDE5A | |
| SCHEMBL4015301 | 0.80 | TACR1 (0.48) | TACR1 | |
| SCHEMBL29891406 | 0.78 | CYP3A4 (0.43) | RIPK1 | |
| SCHEMBL2237484 | 0.77 | PIK3CD (0.48) | RIPK1SCD5SLC6A9PDE5AJAK2 | |
| SCHEMBL27077318 | 0.77 | RIPK1 (0.47) | RIPK1SLC6A9PDE5ATACR1 | |
| SCHEMBL25053385 | 0.75 | RIPK1 (0.41) | RIPK1DRD4MAOAMAOB | |
| SCHEMBL4598879 | 0.75 | RIPK1 (0.47) | RIPK1SCD5NPC1PDE5ANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157285-A | Pharmaceutical compounds as ubiquitin-specific protease 19 (USP 19) inhibitors | 阿尔麦克探索有限公司 | 2023-12-01 | — | — | CN | disclosed |