⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693090 | 0.81 | — | — | |
| SCHEMBL3537101 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL4701756 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3963500 | 0.67 | — | — | |
| Formic Acid SCHEMBL4699651 | 0.63 | — | — | |
| SCHEMBL4658870 | 0.62 | — | — | |
| SCHEMBL4598893 | 0.61 | — | — | |
| SCHEMBL11549187 | 0.60 | — | — | |
| SCHEMBL2638582 | 0.58 | — | — | |
| SCHEMBL20138845 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399424-B8 | METHOD FOR PREPARATION OF 10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE AND 10,11-DIHYDRO-10-0X0-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE | BIAL PORTELA & CA SA (PT) | 2008-10-01 | — | — | EP | disclosed |
| EP-1399424-A1 | METHOD FOR PREPARATION OF 10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE AND 10,11-DIHYDRO-10-0X0-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE | Portela & CA SA (PT) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002096881-A1 | METHOD FOR PREPARATION OF 10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE AND 10,11-DIHYDRO-10-0X0-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE | PORTELA & CA SA (PT) | 2002-12-05 | — | — | WO | disclosed |