Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437989 | 0.85 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL9979414 | 0.85 | — | — | |
| SCHEMBL21085086 | 0.75 | SLC6A12 (0.36) | ALDH1A1 | |
| SCHEMBL28018997 | 0.75 | EPHX1 (0.33) | ALDH1A1 | |
| SCHEMBL906523 | 0.74 | — | — | |
| SCHEMBL1929763 | 0.74 | — | — | |
| SCHEMBL28560664 | 0.74 | — | — | |
| SCHEMBL7115786 | 0.72 | — | — | |
| SCHEMBL21085148 | 0.72 | HSD17B10 (0.30) | ALDH1A1 | |
| SCHEMBL8535090 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910358-A2 | HETEROCYCLIC JANUS KINASE 3 INHIBITORS | Astellas Pharma Inc. (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007007919-A2 | HETEROCYCLIC JANUS KINASE 3 INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2007-01-18 | — | — | WO | disclosed |