⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667495 | 0.89 | LMNA (0.42) | — | |
| SCHEMBL8556930 | 0.85 | LMNA (0.57) | — | |
| SCHEMBL3453066 | 0.83 | — | — | |
| SCHEMBL11355413 | 0.81 | LMNA (0.52) | — | |
| SCHEMBL2355488 | 0.81 | LMNA (0.52) | — | |
| SCHEMBL7559890 | 0.80 | LMNA (0.38) | — | |
| SCHEMBL9459 | 0.80 | — | — | |
| SCHEMBL2094168 | 0.80 | LMNA (1.00) | — | |
| SCHEMBL3504284 | 0.78 | — | — | |
| SCHEMBL2956141 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012123467-A1 | PYRIMIDINE AMIDE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-20 | — | — | WO | disclosed |
| CN-100537575-C | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMITOMO CHEMICAL CO (JP) | 2009-09-09 | — | — | CN | disclosed |
| US-7468448-B2 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| EP-1907347-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | Arcadia Pharmaceuticals Inc. (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007009083-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| US-7141352-B2 | Basic compound, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-11-28 | — | — | US | disclosed |
| CN-1753898-A | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMITOMO CHEMICAL CO (JP) | 2006-03-29 | — | — | CN | disclosed |
| US-20050256322-A1 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1589018-A1 | PROCESS FOR PRODUCING HEXAHYDROFUROFURANOL DERIVATIVE, INTERMEDIATE THEREOF AND PROCESS FOR PRODUCING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2005-10-26 | — | — | EP | disclosed |
| US-6867321-B2 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-03-15 | — | — | US | disclosed |
| US-20050008968-A1 | Basic compound, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
| US-20040162340-A1 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-08-19 | — | — | US | disclosed |
| US-5405977-A | Adsorbing on surface of hydrotalcite | HUNTSMAN CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0258578-B1 | LIQUID CRYSTAL COMPOUNDS HAVING ETHER TAIL MOIETY | POLAROID CORPORATION (US) | 1993-01-07 | — | — | EP | disclosed |