Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355413 | 1.00 | LMNA (0.52) | LMNADNM1THRB | |
| SCHEMBL8556930 | 0.91 | LMNA (0.57) | LMNATHRB | |
| SCHEMBL17936343 | 0.82 | LMNA (0.57) | LMNADNM1THRB | |
| SCHEMBL873415 | 0.82 | LMNA (0.57) | LMNADNM1THRB | |
| SCHEMBL11044298 | 0.82 | LMNA (0.57) | LMNADNM1THRB | |
| SCHEMBL4599059 | 0.81 | — | — | |
| SCHEMBL10004751 | 0.79 | LMNA (0.60) | LMNADNM1THRB | |
| SCHEMBL9197603 | 0.78 | LMNA (0.52) | LMNADNM1THRB | |
| SCHEMBL8837348 | 0.78 | LMNA (0.52) | LMNADNM1THRB | |
| SCHEMBL8899889 | 0.78 | LMNA (0.52) | LMNADNM1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101828552-B | Methods of blocking ethylene response in plants using cyclopropene derivatives | UNIV NORTH CAROLINA STATE | 2014-09-24 | — | — | CN | disclosed |
| CN-101979394-B | A method to inhibit ethylene responses in plants | ROHM & HAAS | 2013-04-03 | — | — | CN | disclosed |
| US-20110190137-A1 | METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | JACOBSON RICHARD MARTIN | 2011-08-04 | — | — | US | disclosed |
| CN-1450859-B | Method for blocking ethylene response in plants using cyclopropene derivatives | UNIV NORTH CAROLINA STATE | 2011-08-03 | — | — | CN | disclosed |
| CN-101979394-A | A method to inhibit ethylene responses in plants | ROHM & HAAS | 2011-02-23 | — | — | CN | disclosed |
| CN-101828552-A | Method with the cyclopropene derivatives blocking ethylene response in plants | UNIV NORTH CAROLINA STATE | 2010-09-15 | — | — | CN | disclosed |
| CN-100475033-C | Cyclopropene supply system | ROHM & HAAS (US) | 2009-04-08 | — | — | CN | disclosed |
| EP-1409440-A4 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM & HAAS (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20050065033-A1 | Method to inhibit ethylene responses in plants | JACOBSON RICHARD MARTIN (US) | 2005-03-24 | — | — | US | disclosed |
| EP-1409440-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| CN-1450859-A | method for blocking ethylene response in plants using cyclopropene derivatives | UNIV NORTH CAROLINA STATE (US) | 2003-10-22 | — | — | CN | disclosed |
| US-6548448-B2 | Delivery systems for cyclopropenes | ROHM AND HAAS COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-20020198107-A1 | Delivery systems for cyclopropenes | AGROFRESH, INC. | 2002-12-26 | — | — | US | disclosed |
| CN-1371603-A | Cyclopropene supply system | ROHM & HAAS (US) | 2002-10-02 | — | — | CN | disclosed |
| WO-2002068367-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
| EP-1236397-A2 | Delivery systems for cyclopropenes | ROHM AND HAAS COMPANY (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-1233669-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6365549-B2 | PRESERVATION | NORTH CAROLINA STATE UNIVERSITY | 2002-04-02 | — | — | US | disclosed |
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | NORTH CAROLINA STATE UNIVERSITY | 2001-09-06 | — | — | US | disclosed |
| WO-2001037663-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | PRUNE1, NOTUM, FAR1 | LMNA 3181/4885DNM1 2713/4885THRB 1839/4885 |
| US-20050065033-A1 | Method to inhibit ethylene responses in plants | ERN1, CTH, CBS | LMNA 4146/4885DNM1 2797/4885THRB 2569/4885 |
| US-20110190137-A1 | METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ERN1, CTH, CBR3 | LMNA 4062/4885DNM1 2664/4885THRB 2555/4885 |
| US-20020198107-A1 | Delivery systems for cyclopropenes | FKBP2, FKBP4, FKBP1A | LMNA 2716/4885DNM1 2806/4885THRB 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.