SCHEMBL4599229

SCHEMBL4599229

CC(C)(C)Nc1[c]ccc(OCc2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.45
ALOX5 P09917 1/20 0.44
BCHE P06276 4/20 0.43
PDK1 Q15118 1/20 0.40
PDK2 Q15119 1/20 0.40
PDK3 Q15120 1/20 0.40
PDK4 Q16654 1/20 0.40
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
MAOA P21397 1/20 0.39
NSD2 O96028 1/20 0.39
ABL1 P00519 1/20 0.39
PPARG P37231 1/20 0.39
RIN1 Q13671 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
NR4A2 P43354 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4600042 0.84 MAOB (0.49) MAOBALOX5BCHECYP4F2CYP4A11
SCHEMBL4599858 0.81 MAOB (0.46) MAOBALOX5BCHECYP4F2CYP4A11
SCHEMBL3456084 0.79 BCHE (0.53) MAOBALOX5BCHEMAOAL3MBTL1
SCHEMBL539028 0.79 MAOB (0.53) MAOBALOX5BCHECYP4F2CYP4A11
SCHEMBL4598481 0.77 BCHE (0.52) MAOBALOX5BCHECYP4F2CYP4A11
SCHEMBL4598684 0.75 BCHE (0.43) MAOBALOX5BCHECYP4F2CYP4A11
SCHEMBL4599932 0.75 BCHE (0.53) MAOBBCHEPPARG
SCHEMBL12883381 0.75 PDK1 (0.57) MAOBBCHEPDK1PDK2PDK3
SCHEMBL2093026 0.73 ALOX5 (0.53) MAOBALOX5BCHECYP4F2CYP4A11
SCHEMBL3948493 0.73 MAOB (0.58) MAOBALOX5BCHECYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910320-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2008-04-16 EP disclosed
WO-2007011065-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-01-25 WO disclosed