SCHEMBL4599247

SCHEMBL4599247

O=C1Oc2ccccc2-c2ccccc2O1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
KDM4E B2RXH2 3/20 0.48
MAPK1 P28482 2/20 0.48
ATM Q13315 1/20 0.48
STK17B O94768 4/20 0.45
PKM P14618 1/20 0.44
TSHR P16473 1/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
CDC25B P30305 2/20 0.43
TYMS P04818 1/20 0.43
HSP90AA1 P07900 1/20 0.41
MAOA P21397 4/20 0.41
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
CES2 O00748 1/20 0.41
APAF1 O14727 1/20 0.41
TERT O14746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5285168 0.82 ALOX15 (0.43) ALOX15TDP1STK17BPKMTSHR
SCHEMBL688738 0.82 TDP1 (0.52) ALOX15TDP1KDM4EMAPK1ATM
SCHEMBL30320031 0.80 TDP1 (0.63) ALOX15TDP1KDM4EMAPK1ATM
SCHEMBL167093 0.80
SCHEMBL12691224 0.80 TDP1 (0.63) ALOX15TDP1KDM4EMAPK1ATM
SCHEMBL19754922 0.80 TDP1 (0.63) ALOX15TDP1KDM4EMAPK1ATM
SCHEMBL19537981 0.79 MAPK1 (0.61) ALOX15TDP1KDM4EMAPK1ATM
SCHEMBL5693983 0.79 MAPK1 (0.61) ALOX15TDP1KDM4EMAPK1ATM
SCHEMBL30567320 0.78 TDP1 (0.68) ALOX15TDP1KDM4EMAPK1ATM
SCHEMBL9057340 0.77 TYMS (0.43) ALOX15TDP1KDM4EMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0063634-A1 Thermoplastic resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1982-11-03 EP claimed
US-4351920-A POLYCARBONATES, RUBBER MODIFIED STYRENE-MALEIC ANHYDRIDE COPOLYMER DAINIPPON INK & CHEMICALS, INC. (JP) 1982-09-28 US claimed
EP-3183026-B1 IMPLANTS FOR LOCALIZED DRUG DELIVERY AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2019-10-30 EP disclosed
EP-3183026-A1 IMPLANTS FOR LOCALIZED DRUG DELIVERY AND METHODS OF USE THEREOF The Regents of The University of California (US) 2017-06-28 EP disclosed
EP-2954035-B1 PROCESS FOR PREPARING A UREA GREASE SHELL INT RESEARCH (NL) 2016-12-21 EP disclosed
WO-2016028774-A1 IMPLANTS FOR LOCALIZED DRUG DELIVERY AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-02-25 WO disclosed
US-20160002557-A1 PROCESS FOR PREPARING A UREA GREASE SHELL OIL COMPANY 2016-01-07 US disclosed
EP-2954035-A1 PROCESS FOR PREPARING A UREA GREASE Shell Internationale Research Maatschappij B.V. (NL) 2015-12-16 EP disclosed
WO-2014122273-A1 PROCESS FOR PREPARING A UREA GREASE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2014-08-14 WO disclosed
EP-1909848-A2 HMGCoA REDUCTASE INHIBITOR CODRUGS AND USES THEREOF PSivida Inc. (US) 2008-04-16 EP disclosed
WO-2007016306-A2 HMGCoA REDUCTASE INHIBITOR CODRUGS AND USES THEREOF PSIVIDA INC. (US) 2007-02-08 WO disclosed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP disclosed
EP-0376311-B1 Photosensitive member for electrophotography CANON KK (JP) 1995-04-05 EP disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5258281-A Light sensitive silver halide multilayer elements with dyes and heat development accelerators CANON KABUSHIKI KAISHA (JP) 1993-11-02 US disclosed
US-5041369-A Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye CANON KABUSHIKI KAISHA (JP) 1991-08-20 US disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0326424-A2 Photosensitive composition, photosensitive material, and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-02 EP disclosed
EP-0063634-A1 Thermoplastic resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1982-11-03 EP disclosed
US-4351920-A POLYCARBONATES, RUBBER MODIFIED STYRENE-MALEIC ANHYDRIDE COPOLYMER DAINIPPON INK & CHEMICALS, INC. (JP) 1982-09-28 US disclosed