SCHEMBL4599252

SCHEMBL4599252

COc1ccc(CNc2[c]ccc(OS(=O)(=O)c3ccc(C)cc3)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
EGFR P00533 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MAOB P27338 1/20 0.41
RAB9A P51151 1/20 0.41
PKM P14618 1/20 0.41
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599161 0.90 HTT (0.49) ALDH1A1CA12CA1CA2CA9
SCHEMBL4599999 0.89 L3MBTL1 (0.45) ALDH1A1CA12CA9HTTLMNA
SCHEMBL3454513 0.82 MEN1 (0.44) ALDH1A1CA12CA2HTTLMNA
SCHEMBL4598731 0.80 ALDH1A1 (0.41) ALDH1A1CA12CA1CA2CA9
SCHEMBL4599126 0.78 MEN1 (0.41) ALDH1A1CA12CA1CA2CA9
SCHEMBL4600277 0.78 MEN1 (0.47) ALDH1A1CA12CA2HTTLMNA
SCHEMBL4599861 0.78 GAA (0.40) ALDH1A1CA12CA9HTTLMNA
SCHEMBL4610582 0.75 ALDH1A1 (0.45) ALDH1A1HTTLMNASMN1; SMN2TDP1
SCHEMBL4599166 0.75 MEN1 (0.44) ALDH1A1CA12CA2HTTLMNA
SCHEMBL27731727 0.74 ALDH1A1 (0.47) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910320-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2008-04-16 EP claimed
WO-2007011065-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-01-25 WO claimed