Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | GPR39 | O43194 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416423 | 1.00 | MAPT (0.51) | MAPTGPR39HTTLMNAMAPK1 | |
| SCHEMBL415522 | 1.00 | MAPT (0.51) | MAPTGPR39HTTLMNAMAPK1 | |
| SCHEMBL10240829 | 0.90 | GPR39 (0.48) | MAPTGPR39HTTLMNAMAPK1 | |
| SCHEMBL413714 | 0.90 | GPR39 (0.48) | MAPTGPR39HTTLMNAMAPK1 | |
| SCHEMBL413715 | 0.90 | GPR39 (0.48) | MAPTGPR39HTTLMNAMAPK1 | |
| SCHEMBL459932 | 0.89 | MAPT (0.43) | MAPTGPR39HTTLMNAMAPK1 | |
| SCHEMBL17836754 | 0.89 | MAPT (0.43) | MAPTGPR39HTTLMNAMAPK1 | |
| SCHEMBL10240830 | 0.86 | MAPT (0.50) | MAPTHTTLMNAMAPK1MEN1 | |
| SCHEMBL418073 | 0.86 | MAPT (0.50) | MAPTHTTLMNAMAPK1MEN1 | |
| SCHEMBL415579 | 0.86 | MAPT (0.50) | MAPTHTTLMNAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |