Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.45 |
| ▸ | RRM1 | P23921 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10948478 | 0.93 | MEN1 (0.48) | EPHX2EPHX1ALDH1A1CYP2C9HPGD | |
| SCHEMBL462123 | 0.89 | EPHX2 (0.55) | EPHX2EPHX1KDM4EALDH1A1MEN1 | |
| SCHEMBL1273832 | 0.86 | EPHX1 (0.58) | EPHX2EPHX1KDM4EMEN1KMT2A | |
| SCHEMBL11594937 | 0.86 | EPHX1 (0.58) | EPHX2EPHX1KDM4EMEN1KMT2A | |
| SCHEMBL11596495 | 0.86 | EPHX1 (0.58) | EPHX2EPHX1KDM4EMEN1KMT2A | |
| SCHEMBL11595110 | 0.86 | EPHX1 (0.58) | EPHX2EPHX1KDM4EMEN1KMT2A | |
| SCHEMBL11594414 | 0.86 | EPHX1 (0.58) | EPHX2EPHX1KDM4EMEN1KMT2A | |
| SCHEMBL11593203 | 0.86 | EPHX1 (0.58) | EPHX2EPHX1KDM4EMEN1KMT2A | |
| SCHEMBL5081267 | 0.86 | EPHX1 (0.58) | EPHX2EPHX1KDM4EMEN1KMT2A | |
| SCHEMBL11596219 | 0.86 | EPHX1 (0.58) | EPHX2EPHX1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653259-B2 | Process for synthesizing heterocyclic compounds | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-02-18 | — | — | US | disclosed |
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | TST, NISCH, CLIC4 | EPHX2 1958/4885DPP7 2518/4885EPHX1 2543/4885 |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | TST, NISCH, CLIC4 | EPHX2 2327/4885DPP7 2894/4885EPHX1 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.