⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403661 | 0.79 | — | — | |
| SCHEMBL936052 | 0.79 | — | — | |
| SCHEMBL16369738 | 0.77 | — | — | |
| Formamide SCHEMBL28176140 | 0.76 | GABRA5 (0.50) | — | |
| SCHEMBL10830273 | 0.76 | HSD17B10 (0.46) | — | |
| SCHEMBL8482071 | 0.75 | — | — | |
| SCHEMBL2667493 | 0.75 | — | — | |
| SCHEMBL14972833 | 0.75 | MAPT (0.51) | — | |
| SCHEMBL3648108 | 0.75 | GABRA5 (0.49) | — | |
| SCHEMBL10904726 | 0.74 | GABRA5 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422843-B1 | 6-0 Methylerythromycin A oxime derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1995-02-15 | — | — | EP | claimed |
| JP-3204893-A | — | — | None | — | — | JP | disclosed |
| US-10544146-B2 | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors | FEDORA PHARMACEUTICALS INC. (CA) | 2020-01-28 | — | — | US | disclosed |
| EP-3360866-B1 | MIRABEGRON PRODRUGS | TIEFENBACHER ALFRED E GMBH & CO KG (DE) | 2019-01-02 | — | — | EP | disclosed |
| US-10030019-B2 | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors | FEDORA PHARMACEUTICALS INC. (CA) | 2018-07-24 | — | — | US | disclosed |
| WO-2016024284-A2 | A PROCESS FOR THE PREPARATION OF MIRABEGRON AND ITS INTERMEDIATES | WANBURY LTD. (IN) | 2016-02-18 | — | — | WO | disclosed |
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| EP-1910342-A1 | MULTICYCLIC SULFONAMIDE COMPOUNDS AS INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE | Kalypsys, Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016354-A1 | MULTICYCLIC SULFONAMIDE COMPOUNDS AS INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| CN-1132756-A | Antiviral ethers of aspartate protease substrate isosteres | CIBA GEIGY AG (CH) | 1996-10-09 | — | — | CN | disclosed |
| US-5302705-A | Effective against Erythromycin-resistant bacteria | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1994-04-12 | — | — | US | disclosed |
| JP-H03204893-A | 6-O-METHYLERYTHROMYCIN A OXIME DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1991-09-06 | — | — | JP | disclosed |
| CN-85105797-A | The preparation of antimicrobial compounds | — | 1986-08-27 | — | — | CN | disclosed |