⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10491859 | 0.88 | HSD17B10 (0.56) | — | |
| SCHEMBL19996122 | 0.80 | NOS1 (0.51) | — | |
| SCHEMBL10403661 | 0.79 | — | — | |
| SCHEMBL4599509 | 0.79 | — | — | |
| SCHEMBL3372234 | 0.77 | — | — | |
| SCHEMBL10830273 | 0.76 | HSD17B10 (0.46) | — | |
| SCHEMBL2408007 | 0.76 | — | — | |
| SCHEMBL19809935 | 0.75 | — | — | |
| SCHEMBL5216503 | 0.73 | GABRA5 (0.40) | — | |
| SCHEMBL2567076 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820436-A1 | SELF-ADHESIVE FLAT PRODUCTS CONTAINING ONE OR MORE ALKYLAMIDOTHIAZOLES | Beiersdorf AG (DE) | 2021-05-19 | — | — | EP | disclosed |
| WO-2020011470-A1 | SELF-ADHESIVE FLAT PRODUCTS CONTAINING ONE OR MORE ALKYLAMIDOTHIAZOLES | BEIERSDORF AG (DE) | 2020-01-16 | — | — | WO | disclosed |
| CN-103906737-B | Alkylamidothiazoles, cosmetic or dermatological preparations containing them and their use for overcoming and preventing undesirable pigmentation of the skin | 拜尔斯道夫股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| US-7868188-B2 | 5-heteroaryl thiazoles and their use as PI3K inhibitors | ASTRAZENECA AB (SE) | 2011-01-11 | — | — | US | disclosed |
| EP-1841763-B1 | 5-HETEROARYL THIAZOLES AND THEIR USE AS PI3K INHIBITORS | ASTRAZENECA AB (SE) | 2010-06-30 | — | — | EP | disclosed |
| US-20080132502-A1 | 5-Heteroaryl Thiazoles And Their Use As PI3K Inhibitors | ASTRAZENECA AB (SE) | 2008-06-05 | — | — | US | disclosed |
| EP-1841763-A1 | 5-HETEROARYL THIAZOLES AND THEIR USE AS PI3K INHIBITORS | AstraZeneca AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| US-7271173-B2 | Mixed kappa/mu opioids and uses thereof | THE MCLEAN HOSPITAL CORPORATION (US) | 2007-09-18 | — | — | US | disclosed |
| WO-2006051270-A1 | 5-HETEROARYL THIAZOLES AND THEIR USE AS P13K INHIBITORS | ASTRAZENECA AB (SE) | 2006-05-18 | — | — | WO | disclosed |
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | MITSUI CHEMICALS, INC. (JP) | 2005-06-30 | — | — | US | disclosed |
| US-20040259901-A1 | Mixed kappa/mu opioids and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-23 | — | — | US | disclosed |
| EP-1489073-A1 | PROCESS FORPREPARATION OF ALKOXYBENZAMIDES AND THIAZOLYL ISOCYANATES | MITSUI CHEMICALS, INC. (JP) | 2004-12-22 | — | — | EP | disclosed |
| WO-2004045562-A2 | MIXED KAPPA/MU OPIOIDS AND USES THEREOF | THE MCLEAN HOSPITAL CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |
| EP-0091220-B1 | THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELI LILLY AND COMPANY (US) | 1987-05-13 | — | — | EP | disclosed |