Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.34 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117814 | 0.87 | PLOD2 (0.59) | CES2CES1PLOD2ALDH1A1MAPT | |
| SCHEMBL10873114 | 0.78 | CES2 (0.47) | CES2CES1PLOD2MAPTPOLB | |
| SCHEMBL4599899 | 0.76 | PLOD2 (0.73) | CES2CES1PLOD2MAPTPTPN1 | |
| SCHEMBL17921197 | 0.75 | CES2 (0.55) | CES2CES1ALDH1A1MAPTMDM2 | |
| SCHEMBL25204030 | 0.73 | CES2 (0.53) | CES2CES1ALDH1A1MAPTMDM2 | |
| SCHEMBL1924321 | 0.73 | PLOD2 (0.59) | CES2CES1PLOD2MAPTPOLB | |
| SCHEMBL27764538 | 0.73 | CES2 (0.63) | CES2CES1ALDH1A1MAPTMDM2 | |
| SCHEMBL21509855 | 0.73 | CES2 (0.63) | CES2CES1ALDH1A1MAPTMDM2 | |
| SCHEMBL8911819 | 0.73 | PLOD2 (0.49) | CES2CES1PLOD2MAPTPTPN1 | |
| SCHEMBL3094911 | 0.72 | CES2 (0.61) | CES2CES1ALDH1A1MAPTMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381567-B2 | Dissociative fluorescence enhancement assay | WALLAC OY (FI) | 2008-06-03 | — | — | US | disclosed |
| EP-1483582-B1 | DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY | WALLAC OY (FI) | 2008-04-16 | — | — | EP | disclosed |
| US-7211440-B2 | Dissociative fluorescence enhancement assay | WALLAC OY (FI) | 2007-05-01 | — | — | US | disclosed |
| US-20070015284-A1 | Dissociative fluorescence enhancement assay | HEMMILA ILKKA | 2007-01-18 | — | — | US | disclosed |
| EP-1483582-A1 | DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY | WALLAC OY (FI) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003076939-A1 | DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY | WALLAC OY (FI) | 2003-09-18 | — | — | WO | disclosed |
| US-20030170907-A1 | Dissociative fluorescence enhancement assay | WALLAC OY (FI) | 2003-09-11 | — | — | US | disclosed |