Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839297 | 0.82 | POLB (0.38) | ALDH1A1 | |
| SCHEMBL21564360 | 0.81 | HPGD (0.45) | GAAMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL31082333 | 0.81 | HPGD (0.45) | GAAMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3154922 | 0.79 | SMN1; SMN2 (0.50) | CYP3A4CYP2C19L3MBTL1ALDH1A1 | |
| SCHEMBL16530180 | 0.79 | MAPT (0.44) | CYP3A4CYP2C19GAAMAPTL3MBTL1 | |
| SCHEMBL13889046 | 0.78 | METAP2 (0.45) | L3MBTL1THRBATMALDH1A1 | |
| SCHEMBL27793398 | 0.78 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL21550954 | 0.76 | AKR1C3 (0.47) | ALDH1A1 | |
| SCHEMBL21564359 | 0.76 | CPN1 (0.44) | CYP3A4CYP2C19GAAMAPTL3MBTL1 | |
| SCHEMBL784840 | 0.76 | GAA (0.44) | GAAMAPTL3MBTL1THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910290-A2 | GPCR AGONISTS | Prosidion Limited (GB) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007003962-A2 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |