Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968076 | 0.87 | HPRT1 (0.58) | CHATALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL1971147 | 0.82 | HSD17B10 (0.48) | CHATALDH1A1CYP2A6MTNR1AMTNR1B | |
| SCHEMBL1681129 | 0.81 | CHAT (0.55) | CHATMTNR1AMTNR1BRXRAPTGS1 | |
| SCHEMBL29693644 | 0.81 | CHAT (0.55) | CHATMTNR1AMTNR1BRXRAPTGS1 | |
| SCHEMBL612947 | 0.81 | CHAT (0.55) | CHATMTNR1AMTNR1BRXRAPTGS1 | |
| SCHEMBL272577 | 0.81 | CHAT (0.55) | CHATMTNR1AMTNR1BRXRAPTGS1 | |
| SCHEMBL29563633 | 0.81 | CHAT (0.55) | CHATMTNR1AMTNR1BRXRAPTGS1 | |
| SCHEMBL303721 | 0.79 | ALDH1A1 (0.46) | CHATALDH1A1CYP2A6PTGS1PTGS2 | |
| SCHEMBL816177 | 0.79 | TSHR (0.50) | CHATALDH1A1CYP2A6MTNR1AMTNR1B | |
| SCHEMBL2494362 | 0.79 | TSHR (0.50) | CHATALDH1A1CYP2A6MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13221 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324824-A | Multifunctional chiral multidentate phosphine ligand, preparation and application thereof | 凯特立斯（深圳）科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-114981253-B | Process and intermediates for preparing chroman compounds and methods therefor | 印度鲁宾有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118184681-A | Spiro 1,2, 4-triazole carbene metal complex, intermediate, preparation method and application thereof | 浙江工业大学 | 2024-06-14 | — | — | CN | claimed |
| CN-114929680-B | Process for preparing chroman compounds | 印度鲁宾有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117567332-A | Method for simultaneously synthesizing thioether compounds and nitrile compounds | 石河子大学 | 2024-02-20 | — | — | CN | claimed |
| CN-116848094-A | Tertiary amine lipid compounds and uses thereof | 华南理工大学 | 2023-10-03 | — | — | CN | claimed |
| WO-2023125184-A1 | TERTIARY AMINE LIPID COMPOUND AND USE THEREOF | 华南理工大学 | 2023-07-06 | — | — | WO | claimed |
| CN-116120919-A | Triplet-triplet annihilation up-conversion luminescent material based on thermal activation and preparation and application thereof | 中国科学院理化技术研究所 | 2023-05-16 | — | — | CN | claimed |
| US-11530234-B2 | CD73 inhibitors and pharmaceutical uses thereof | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-12-20 | — | — | US | claimed |
| CN-111253739-B | DOPO derivative/carbon nanotube synergistic flame-retardant glass fiber nylon composite material | 贵州省材料产业技术研究院(贵州省复合改性聚合物材料工程技术研究中心、国家复合改性聚合物材料工程技术研究中心) | 2022-12-02 | — | — | CN | claimed |
| EP-0044158-B1 | NOVEL OPTICALLY ACTIVE IMIDAZOLIDIN-2-ONE DERIVATIVES AND THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-15 | — | — | EP | claimed |
| EP-0106652-A1 | Beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-04-25 | — | — | EP | claimed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | claimed |
| US-4366102-A | Process for the preparation of chloroformic acid aryl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1982-12-28 | — | — | US | claimed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | claimed |
| EP-0044158-A1 | Novel optically active imidazolidin-2-one derivatives and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-20 | — | — | EP | claimed |
| US-4261988-A | ANTICHOLESTEROL AGENTS USED IN ANIMAL HUSBANDRY | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-14 | — | — | US | claimed |
| US-4206295-A | Process of preparing poly[{alkyl-(3-ammoniopropyl)iminio}trimethylene dihalides] | MERCK & CO., INC. (US) | 1980-06-03 | — | — | US | claimed |
| US-4158016-A | CONTACTING WITH AN ALKALI METAL POLYCYCLIC AROMATIC HYDROCARBON CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-06-12 | — | — | US | claimed |
| US-4119726-A | ANTISECRETORY AGENTS, BRONCHODILATORS, ANTICOAGULANTS | BEECHAM GROUP LIMITED (GB) | 1978-10-10 | — | — | US | claimed |