Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320552 | 1.00 | HCAR3 (0.40) | HCAR3HCAR2CES2CES1CYP1A2 | |
| SCHEMBL29992337 | 0.81 | TSHR (0.39) | CYP1A2TP53TSHRMEN1KMT2A | |
| SCHEMBL11016310 | 0.79 | AKR1C1 (0.41) | HCAR3HCAR2CYP1A2AKR1C1TSHR | |
| SCHEMBL320551 | 0.76 | HCAR3 (0.41) | HCAR3HCAR2CYP1A2AKR1C1TSHR | |
| SCHEMBL19809338 | 0.72 | MEN1 (0.36) | HCAR3HCAR2CYP1A2MAPTTP53 | |
| SCHEMBL9817499 | 0.71 | HCAR3 (0.40) | HCAR3HCAR2CYP1A2AKR1C1TSHR | |
| SCHEMBL10795202 | 0.71 | HCAR3 (0.40) | HCAR3HCAR2CYP1A2AKR1C1TSHR | |
| SCHEMBL27320951 | 0.69 | HCAR3 (0.40) | HCAR3HCAR2CYP1A2AKR1C1TSHR | |
| SCHEMBL9692257 | 0.69 | MEN1 (0.45) | HCAR3HCAR2MAPTTSHRMEN1 | |
| SCHEMBL11211886 | 0.69 | AKR1C1 (0.33) | HCAR3HCAR2CYP1A2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909599-A1 | USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE | Symrise GmbH & Co. KG (DE) | 2008-04-16 | — | — | EP | claimed |
| WO-2007014879-A1 | USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE | SYMRISE GMBH & CO. KG (DE) | 2007-02-08 | — | — | WO | claimed |