Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320551 | 0.84 | HCAR3 (0.41) | HCAR3HCAR2CYP1A2AKR1C1TSHR | |
| SCHEMBL18338919 | 0.76 | OPRM1 (0.47) | KMT2AMEN1MITFSLC6A4GAA | |
| SCHEMBL11417195 | 0.73 | FFAR3 (0.35) | — | |
| SCHEMBL9817499 | 0.71 | HCAR3 (0.40) | HCAR3HCAR2CYP1A2AKR1C1TSHR | |
| SCHEMBL320552 | 0.71 | HCAR3 (0.40) | HCAR3HCAR2CYP1A2AKR1C1TSHR | |
| SCHEMBL4600241 | 0.71 | HCAR3 (0.40) | HCAR3HCAR2CYP1A2AKR1C1TSHR | |
| SCHEMBL3141154 | 0.70 | HCAR2 (0.43) | HCAR2TSHRKMT2AMEN1LMNA | |
| SCHEMBL24400590 | 0.69 | ALDH1A1 (0.38) | HCAR3HCAR2CYP1A2SIRT1TSHR | |
| SCHEMBL17599606 | 0.69 | FFAR3 (0.32) | LMNA | |
| SCHEMBL3132501 | 0.69 | HCAR2 (0.43) | HCAR2TSHRKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716226-A | Optically active 4-carbalkoxy-2-azetidinones | ROUSSEL UCLAF (FR) | 1987-12-29 | — | — | US | disclosed |