Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | Q9HBH1 | 1/20 | 0.42 | |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738732 | 0.87 | CA1 (0.51) | PLGMMP2MMP9 | |
| SCHEMBL4738722 | 0.87 | CA1 (0.51) | PLGMMP2MMP9 | |
| SCHEMBL4738726 | 0.87 | CA1 (0.51) | PLGMMP2MMP9 | |
| SCHEMBL7419417 | 0.84 | ANPEP (0.49) | PLGKLKB1PDF | |
| SCHEMBL14111113 | 0.82 | LTA4H (0.66) | NPC1RAB9ASMN1; SMN2SSTR3LTA4H | |
| SCHEMBL4599805 | 0.77 | FPR2 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2MMP2 | |
| SCHEMBL4599812 | 0.77 | FPR2 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2MMP2 | |
| SCHEMBL4599798 | 0.77 | FPR2 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2MMP2 | |
| SCHEMBL13684815 | 0.77 | SSTR3 (0.56) | SMN1; SMN2PLGMMP2SSTR3MMP1 | |
| Hydrochloric Acid SCHEMBL7036448 | 0.77 | SSTR3 (0.51) | PLGMMP2SSTR3MMP1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |