Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 4/20 | 0.38 |
| ▸ | RET | P07949 | 10/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470601 | 0.88 | NTRK1 (0.38) | NTRK1RET | |
| SCHEMBL460034 | 0.87 | CHRM2 (0.38) | NTRK1RETCTSKUSP30AAK1 | |
| SCHEMBL470564 | 0.86 | NTRK1 (0.36) | NTRK1RET | |
| SCHEMBL12064739 | 0.85 | NTRK1 (0.35) | NTRK1RET | |
| SCHEMBL470608 | 0.85 | NTRK1 (0.37) | NTRK1RET | |
| SCHEMBL470523 | 0.84 | NTRK1 (0.35) | NTRK1RET | |
| SCHEMBL12064782 | 0.84 | PDE4B (0.42) | NTRK1 | |
| SCHEMBL12064744 | 0.84 | NTRK1 (0.34) | NTRK1RET | |
| SCHEMBL14723139 | 0.83 | USP30 (0.41) | NTRK1RETCTSKUSP30AAK1 | |
| SCHEMBL14723138 | 0.83 | USP30 (0.41) | NTRK1RETCTSKUSP30AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |