Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.38 |
| ▸ | RET | P07949 | 9/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460032 | 0.87 | NTRK1 (0.38) | NTRK1RETCTSKAAK1USP30 | |
| SCHEMBL14723139 | 0.83 | USP30 (0.41) | NTRK1RETCTSKAAK1USP30 | |
| SCHEMBL14723138 | 0.83 | USP30 (0.41) | NTRK1RETCTSKAAK1USP30 | |
| SCHEMBL470485 | 0.83 | GPR119 (0.43) | CHRM2NTRK1RET | |
| SCHEMBL609161 | 0.82 | AAK1 (0.41) | CHRM2NTRK1RETAAK1 | |
| SCHEMBL459423 | 0.81 | GPR119 (0.41) | NTRK1RET | |
| SCHEMBL470735 | 0.80 | NTRK1 (0.42) | NTRK1RET | |
| SCHEMBL148182 | 0.80 | NTRK1 (0.38) | NTRK1RET | |
| SCHEMBL148181 | 0.80 | NTRK1 (0.38) | NTRK1RET | |
| SCHEMBL458011 | 0.80 | ACACB (0.35) | RETACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |