Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 5/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 6/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064744 | 0.95 | NTRK1 (0.34) | NTRK1NR1H2ALOX5APRETGPR119 | |
| SCHEMBL12064745 | 0.95 | NTRK1 (0.34) | NTRK1NR1H2ALOX5APRETKDM4D | |
| SCHEMBL12064814 | 0.94 | NR1H2 (0.33) | NR1H2ALOX5APRETGPR119EIF2AK4 | |
| SCHEMBL462819 | 0.89 | NTRK1 (0.34) | NTRK1NR1H2RETGPR119 | |
| SCHEMBL470486 | 0.88 | NTRK1 (0.36) | NTRK1NR1H2RETKDM4DGPR119 | |
| SCHEMBL470798 | 0.88 | DPP4 (0.32) | NR1H2ALOX5APGPR119KCNH2 | |
| SCHEMBL12064983 | 0.86 | GPR119 (0.36) | NR1H2GPR119KCNH2 | |
| SCHEMBL470535 | 0.86 | NR1H2 (0.33) | NR1H2RETEIF2AK4CKS1BSKP1 | |
| SCHEMBL470580 | 0.86 | NR1H2 (0.33) | NR1H2RETEIF2AK4CKS1BSKP1 | |
| SCHEMBL470549 | 0.86 | ALOX5AP (0.30) | ALOX5APCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |