Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL3 | P20749 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614085 | 0.82 | CD274 (0.56) | ALDH1A1 | |
| SCHEMBL8167729 | 0.76 | KMT2A (0.66) | BCL3ALDH1A1MEN1KMT2A | |
| SCHEMBL16430973 | 0.73 | POLB (0.87) | BCL3ALDH1A1GAAHTTKMT2A | |
| SCHEMBL29849958 | 0.73 | POLB (0.87) | BCL3ALDH1A1GAAHTTKMT2A | |
| SCHEMBL31298077 | 0.72 | KMT2A (0.67) | BCL3ALDH1A1KDM5BMEN1KMT2A | |
| SCHEMBL4600038 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL17554115 | 0.72 | POLB (0.69) | BCL3ALDH1A1KDM5BGAAHTT | |
| SCHEMBL29849775 | 0.72 | BCL3 (1.00) | BCL3ALDH1A1GAAHTTKMT2A | |
| SCHEMBL16431474 | 0.72 | BCL3 (0.76) | BCL3ALDH1A1GAAHTTMEN1 | |
| SCHEMBL17554105 | 0.72 | HTT (0.82) | BCL3ALDH1A1GAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912959-A2 | 5-SUBSTITUTED THIAZOL-2-YL AMINO COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-04-23 | — | — | EP | claimed |
| WO-2007016228-A2 | 5-SUBSTITUTED THIAZOL-2-YL AMINO COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2007-02-08 | — | — | WO | claimed |