Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 3/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600014 | 1.00 | ITGA4 (0.35) | ITGA4ITGB7PPARGPPARAANPEP | |
| SCHEMBL4599268 | 1.00 | ITGA4 (0.35) | ITGA4ITGB7PPARGPPARAANPEP | |
| SCHEMBL1062783 | 0.85 | SLC7A5 (0.38) | ITGA4ITGB7PPARGPPARASLC7A5 | |
| SCHEMBL19899292 | 0.83 | ATM (0.41) | MAPTTDP1ACEATMCTSS | |
| SCHEMBL4599009 | 0.83 | PPARG (0.42) | PPARGPPARAACEATMPTPN1 | |
| SCHEMBL30510366 | 0.83 | CTRB1 (0.40) | ITGA4PPARGPPARAMAPTITGB1 | |
| SCHEMBL4600067 | 0.83 | CTRB1 (0.40) | ITGA4PPARGPPARAMAPTITGB1 | |
| SCHEMBL5407004 | 0.83 | CTRB1 (0.40) | ITGA4PPARGPPARAMAPTITGB1 | |
| SCHEMBL4600752 | 0.83 | CTRB1 (0.40) | ITGA4PPARGPPARAMAPTITGB1 | |
| SCHEMBL7338794 | 0.82 | ITGA4 (0.39) | ITGA4ITGB7CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080223-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-10 | — | — | WO | disclosed |
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |