Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 2/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.66 |
| ▸ | CA5A | P35218 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724835 | 0.78 | CA12 (0.74) | CA12CA1CA2CA14CA5A | |
| SCHEMBL14893135 | 0.77 | MTNR1A (0.74) | CA12CA1CA2CA14CA5A | |
| SCHEMBL3202320 | 0.77 | CA12 (0.63) | CA12CA1CA2CA14CA5A | |
| SCHEMBL4556504 | 0.74 | MTNR1A (0.61) | CA12CA1CA2CA14CA5A | |
| SCHEMBL169897 | 0.74 | MTNR1A (0.70) | CA12CA1CA2CA14CA5A | |
| SCHEMBL14241869 | 0.73 | MTNR1A (0.72) | CA12CA1CA2CA14CA5A | |
| SCHEMBL1010724 | 0.72 | MTNR1A (1.00) | MTNR1AMTNR1BTAAR1CNR1HPGD | |
| SCHEMBL11896371 | 0.72 | MTNR1A (0.77) | CA12CA1CA2CA14CA5A | |
| SCHEMBL16244485 | 0.72 | TAAR1 (0.56) | CA12CA1CA2CA14CA5A | |
| SCHEMBL21550403 | 0.72 | L3MBTL1 (0.63) | CA12CA1CA2CA14CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |