Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8320325 | 0.98 | APLNR (0.58) | APLNRCYP1A2TSHRGRM2GRM3 | |
| SCHEMBL17212627 | 0.86 | APLNR (0.65) | APLNRCYP1A2TSHRGRM2GRM3 | |
| SCHEMBL23590185 | 0.86 | APLNR (0.65) | APLNRCYP1A2TSHRGRM2GRM3 | |
| SCHEMBL8318891 | 0.86 | APLNR (0.65) | APLNRCYP1A2TSHRGRM2GRM3 | |
| 3-Methylbutanoic Acid SCHEMBL28165074 | 0.85 | APLNR (0.44) | APLNRCYP1A2TSHRGRM2GRM3 | |
| SCHEMBL8933185 | 0.84 | APLNR (0.44) | APLNRCYP1A2HSD11B1 | |
| SCHEMBL30879578 | 0.83 | APLNR (0.43) | APLNRCYP1A2HSD11B1GABRPGABRD | |
| SCHEMBL715584 | 0.83 | APLNR (0.43) | APLNRCYP1A2HSD11B1GABRPGABRD | |
| SCHEMBL23457777 | 0.83 | APLNR (0.43) | APLNRCYP1A2HSD11B1GABRPGABRD | |
| SCHEMBL28598649 | 0.81 | APLNR (0.41) | APLNRCYP1A2LMNATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140171295-A1 | CATALYST COMPOSITION AND PROCESS USING SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2014-06-19 | — | — | US | claimed |
| EP-1913048-A1 | CATALYST COMPOSITION AND PROCESS USING SAME | Momentive Performance Materials Inc. (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2006138050-A1 | CATALYST COMPOSITION AND PROCESS USING SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2006-12-28 | — | — | WO | claimed |
| US-20060281827-A1 | Catalyst composition and process using same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-12-14 | — | — | US | claimed |
| CN-110790981-B | PVC plasticizer and preparation method thereof | 克拉通聚合物研究有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2023154344-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| US-10927234-B2 | PVC plasticizers and methods for making thereof | KRATON POLYMERS U.S. LLC (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200040160-A1 | PVC Plasticizers and Methods for Making Thereof | KRATON POLYMERS LLC (US) | 2020-02-06 | — | — | US | disclosed |
| EP-3604418-A1 | PVC PLASTICIZERS AND METHODS FOR MAKING THEREOF | Kraton Polymers Research B.V. (NL) | 2020-02-05 | — | — | EP | disclosed |
| EP-3275962-B1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2019-10-02 | — | — | EP | disclosed |
| US-20190218367-A1 | PVC Plasticizers and Methods for Making Thereof | KRATON POLYMERS LLC (US) | 2019-07-18 | — | — | US | disclosed |
| WO-2016106623-A1 | BENZAMIDE IMIDAZOPYRAZINE BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| US-8729146-B2 | Catalyst composition and process using same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-05-20 | — | — | US | disclosed |
| EP-1913048-A1 | CATALYST COMPOSITION AND PROCESS USING SAME | Momentive Performance Materials Inc. (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2006138050-A1 | CATALYST COMPOSITION AND PROCESS USING SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060281827-A1 | Catalyst composition and process using same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-12-14 | — | — | US | disclosed |
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| CN-1042335-C | 1-acylpiperidine compounds | NORVATIS AG (CH) | 1999-03-03 | — | — | CN | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |
| CN-1089261-A | The 1-acylpiperidine compounds | CIBA GEIGY AG (CH) | 1994-07-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927234-B2 | PVC plasticizers and methods for making thereof | DDT, FASN, FDFT1 | APLNR 415/4885CYP1A2 978/4885TSHR 1812/4885 |
| US-20190218367-A1 | PVC Plasticizers and Methods for Making Thereof | DDT, FASN, FDFT1 | APLNR 415/4885CYP1A2 978/4885TSHR 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.