SCHEMBL8933185

SCHEMBL8933185

CC1(C)CCCC(C(=O)C2CCCC(C)(C)C2)C1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.44
HSD11B1 P28845 1/20 0.34
CYP1A2 P05177 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27900264 0.86 APLNR (0.48) APLNRCYP1A2
SCHEMBL23457777 0.84 APLNR (0.43) APLNRHSD11B1CYP1A2CES2CES1
SCHEMBL30879578 0.84 APLNR (0.43) APLNRHSD11B1CYP1A2CES2CES1
SCHEMBL715584 0.84 APLNR (0.43) APLNRHSD11B1CYP1A2CES2CES1
SCHEMBL4600499 0.84 APLNR (0.60) APLNRHSD11B1CYP1A2
Hydrochloric Acid SCHEMBL8320325 0.83 APLNR (0.58) APLNRHSD11B1CYP1A2
SCHEMBL28598649 0.83 APLNR (0.41) APLNRHSD11B1CYP1A2
SCHEMBL15541036 0.83 APLNR (0.41) APLNRHSD11B1CYP1A2
SCHEMBL15541347 0.83 APLNR (0.41) APLNRHSD11B1CYP1A2
Hydrochloric Acid SCHEMBL16738264 0.81 APLNR (0.40) APLNRHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104024258-B Pyrrolopyrazine kinase inhibitors 霍夫曼-拉罗奇有限公司 2017-02-15 CN disclosed
CN-103189076-A Deodorant composition for sulfides TAKASAGO PERFUMERY CO LTD 2013-07-03 CN disclosed
CN-102171321-A Aromatic composition KOBAYASHI PHARMA 2011-08-31 CN disclosed
CN-100376292-C Deodorant composition TAKASAGO PERFUMERY CO LTD (JP) 2008-03-26 CN disclosed
CN-1732019-A Deodorant composition TAKASAGO PERFUMERY CO LTD (JP) 2006-02-08 CN disclosed
CN-1198839-C Novel dipeptide amidines as thrombin inhibitors AIBET GMBH & CO KG (DE) 2005-04-27 CN disclosed
CN-1175953-A Novel dipeptide amidines as thrombin inhibitors BASF AG (DE) 1998-03-11 CN disclosed
WO-1996025426-A1 NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1996-08-22 WO disclosed