Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324059 | 0.84 | KCNN4 (0.56) | KCNN4TAAR1CYP1A2CYP2D6MAPT | |
| SCHEMBL27579783 | 0.81 | PIN1 (0.49) | KCNN4TAAR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1624876 | 0.81 | CYP2C19 (0.44) | KCNN4TAAR1CYP1A2CYP2D6KIF11 | |
| SCHEMBL1081535 | 0.80 | CYP1A2 (0.47) | KCNN4TAAR1CYP1A2CYP2D6KIF11 | |
| SCHEMBL9293537 | 0.80 | ALDH1A1 (0.47) | CYP1A2CYP2D6KMT2ACYP2C19 | |
| SCHEMBL8762498 | 0.80 | ALDH1A1 (0.47) | CYP1A2CYP2D6KMT2ACYP2C19 | |
| SCHEMBL9293536 | 0.80 | ALDH1A1 (0.47) | CYP1A2CYP2D6KMT2ACYP2C19 | |
| Acetic Acid SCHEMBL23121530 | 0.78 | CYP2C19 (0.42) | KCNN4TAAR1CYP1A2CYP2D6KIF11 | |
| SCHEMBL1083233 | 0.76 | KCNN4 (0.45) | KCNN4CYP1A2CYP2D6KIF11MAPT | |
| SCHEMBL11778673 | 0.76 | KCNN4 (0.45) | KCNN4CYP1A2CYP2D6KIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080223-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-10 | — | — | WO | disclosed |
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |