Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.65 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.31 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600547 | 0.89 | CNR1 (0.69) | CNR1MALT1NR1H4P2RX7CACNA1B | |
| SCHEMBL4247679 | 0.81 | CNR1 (0.57) | CNR1HSD17B10TDP1GAACTSA | |
| SCHEMBL4679409 | 0.79 | CNR1 (1.00) | CNR1NR1H4GSK3BDYRK1A | |
| SCHEMBL4599782 | 0.76 | CNR1 (0.42) | CNR1CACNA1BAPAF1HPGDAPBA1 | |
| SCHEMBL4677342 | 0.75 | CNR1 (0.69) | CNR1 | |
| SCHEMBL4681021 | 0.74 | CNR1 (0.57) | CNR1ALDH1A1GAASMN1; SMN2PTGDR2 | |
| SCHEMBL4247678 | 0.71 | CNR1 (0.57) | CNR1ALDH1A1SMN1; SMN2PTGDR2 | |
| SCHEMBL4243036 | 0.71 | CNR1 (0.48) | CNR1SMN1; SMN2PTGDR2 | |
| SCHEMBL4680862 | 0.70 | CNR1 (0.59) | CNR1ALDH1A1SMN1; SMN2PTGDR2 | |
| SCHEMBL4242266 | 0.69 | CNR1 (0.73) | CNR1MALT1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910304-A2 | THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007010222-A2 | THERAPEUTIC AGENTS | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | WO | disclosed |