Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.69 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.33 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.33 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600541 | 0.89 | CNR1 (0.65) | CNR1MALT1CACNB4CACNA1ACACNA1G | |
| SCHEMBL4247679 | 0.84 | CNR1 (0.57) | CNR1SLC2A1 | |
| SCHEMBL4679409 | 0.78 | CNR1 (1.00) | CNR1NR1H4 | |
| SCHEMBL4243036 | 0.73 | CNR1 (0.48) | CNR1SLC2A1 | |
| SCHEMBL4677342 | 0.72 | CNR1 (0.69) | CNR1 | |
| SCHEMBL4681021 | 0.72 | CNR1 (0.57) | CNR1SLC2A1 | |
| SCHEMBL4242266 | 0.71 | CNR1 (0.73) | CNR1MALT1NR1H4 | |
| SCHEMBL4247678 | 0.69 | CNR1 (0.57) | CNR1SLC2A1 | |
| SCHEMBL4680862 | 0.68 | CNR1 (0.59) | CNR1 | |
| SCHEMBL4245861 | 0.66 | CNR1 (0.41) | CNR1MALT1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910304-A2 | THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007010222-A2 | THERAPEUTIC AGENTS | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | WO | disclosed |