SCHEMBL4600671

SCHEMBL4600671

Clc1[nH]c2ccccc2c1Br

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
GPR3 P46089 2/20 0.52
HSD17B10 Q99714 2/20 0.52
NR4A2 P43354 1/20 0.46
KDM4E B2RXH2 5/20 0.44
AHR P35869 2/20 0.44
LMNA P02545 2/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
ATM Q13315 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KMT2A Q03164 4/20 0.41
PARP1 P09874 2/20 0.41
MEN1 O00255 2/20 0.41
CYP1A2 P05177 2/20 0.41
TNKS2 Q9H2K2 2/20 0.41
TNKS O95271 1/20 0.41
BLM P54132 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL7157221 0.88 NR4A2 (0.46) ALDH1A1GPR3HSD17B10NR4A2KDM4E
SCHEMBL29766929 0.78 ALDH1A1 (0.55) ALDH1A1GPR3HSD17B10KDM4EAHR
SCHEMBL1021516 0.78 ALDH1A1 (0.55) ALDH1A1GPR3HSD17B10NR4A2KDM4E
SCHEMBL3197310 0.78 ALDH1A1 (0.55) ALDH1A1GPR3HSD17B10KDM4EAHR
SCHEMBL30981725 0.76 ALDH1A1 (0.52) ALDH1A1GPR3HSD17B10NR4A2KDM4E
SCHEMBL30023276 0.74 ALDH1A1 (0.50) ALDH1A1GPR3HSD17B10KDM4EAHR
SCHEMBL30783368 0.74 AHR (0.61) ALDH1A1GPR3HSD17B10NR4A2KDM4E
SCHEMBL5706426 0.74 ALDH1A1 (0.50) ALDH1A1GPR3HSD17B10KDM4EAHR
SCHEMBL6817362 0.74 AHR (0.61) ALDH1A1GPR3HSD17B10NR4A2KDM4E
SCHEMBL1757709 0.74 AHR (0.61) ALDH1A1GPR3HSD17B10NR4A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254771-A2 Detection of microbes in a sample Edberg, Stephen C. (US) 1988-02-03 EP claimed
CN-118271444-A WNT-substituted molecules and uses thereof 瑟罗泽恩奥普瑞汀公司 2024-07-02 CN disclosed
CN-111699003-B Anti-LRP 5/6 antibodies and methods of use 瑟罗泽恩奥普瑞汀公司 2024-05-03 CN disclosed
CN-117946267-A Anti-frizzled antibodies and methods of use 瑟罗泽恩奥普瑞汀公司 2024-04-30 CN disclosed
CN-111727203-B WNT-substituted molecules and uses thereof 瑟罗泽恩奥普瑞汀公司 2024-04-26 CN disclosed
CN-111655729-B Anti-Frizzled Antibodies and Methods of Use 瑟罗泽恩奥普瑞汀公司 2023-10-20 CN disclosed
CN-107090486-B Articles and methods for detecting target microorganisms 3M创新有限公司 2021-09-03 CN disclosed
CN-103282513-B Articles and methods for detecting target microorganisms 3M创新有限公司 2016-11-16 CN disclosed
CN-103282513-A Articles and methods for detecting target microorganisms 3M INNOVATIVE PROPERTIES CO 2013-09-04 CN disclosed
EP-1528106-B1 Medium for detecting target microbes in a sample IDEXX LAB INC (US) 2008-04-23 EP disclosed
WO-1996014432-A2 MEDIUM FOR DETECTING TARGET MICROBES IN A SAMPLE IDEXX LABORATORIES, INC. (US) 1996-05-17 WO disclosed
WO-1996007669-A1 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES ROSE-HIATT BIOTECHNOLOGY PARTNERSHIP (US) 1996-03-14 WO disclosed
WO-1995015740-A1 OPTIONALLY CROSSLINKABLE COATINGS, COMPOSITIONS AND METHODS OF USE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-15 WO disclosed
WO-1994004196-A1 TUMOUR THERAPY IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 1994-03-03 WO disclosed
EP-0554273-A1 A PROCESS FOR THE GENE MANIPULATION OF PLANT CELLS, RECOMBINANT PLASMIDS, RECOMBINANT BACTERIA, PLANTS CLOVIS MATTON N.V. (BE) 1993-08-11 EP disclosed
CN-1020752-C VACCINES AND IMMUNOASSAYS FOR ACQUIRED IMMUNE DEFICIENCY SYNDROME ONCOGEN (US) 1993-05-19 CN disclosed
EP-0521318-A2 Hepatitis C diagnostics and vaccines LUCKY LTD. (KR) 1993-01-07 EP disclosed
WO-1992022655-A1 HEPATITIS C DIAGNOSTICS AND VACCINES LUCKY LIMITED (KR) 1992-12-23 WO disclosed
WO-1992006205-A1 A PROCESS FOR THE GENE MANIPULATION OF PLANT CELLS, RECOMBINANT PLASMIDS, RECOMBINANT BACTERIA, PLANTS CLOVIS MATTON N.V. (BE) 1992-04-16 WO disclosed
CN-86106632-A Acquired Immunodeficiency Syndrome (AIDS) Vaccine 1987-05-13 CN disclosed