Phosphoric Acid

Phosphoric Acid

SCHEMBL7157221

Clc1[nH]c2ccccc2c1Br.O=P(O)(O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.46
ALDH1A1 P00352 7/20 0.41
GPR3 P46089 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 9/20 0.41
LMNA P02545 4/20 0.41
HTT P42858 2/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
ATM Q13315 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 3/20 0.39
IDE P14735 1/20 0.39
MPI P34949 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
KMT2A Q03164 4/20 0.38
PARP1 P09874 2/20 0.38
MEN1 O00255 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4600671 0.88 ALDH1A1 (0.52) NR4A2ALDH1A1GPR3HSD17B10KDM4E
Phosphoric Acid SCHEMBL7161584 0.84 NR4A2 (0.39) NR4A2ALDH1A1GPR3HSD17B10KDM4E
Phosphoric Acid SCHEMBL29246274 0.83 ALDH1A1 (0.43) ALDH1A1GPR3HSD17B10KDM4ELMNA
Phosphoric Acid SCHEMBL27909978 0.81 KDM4E (0.52) NR4A2ALDH1A1GPR3HSD17B10KDM4E
Phosphoric Acid SCHEMBL8603396 0.80 KDM4E (0.40) NR4A2ALDH1A1GPR3HSD17B10KDM4E
SCHEMBL27564194 0.78 NR4A2 (0.46) NR4A2ALDH1A1GPR3HSD17B10KDM4E
Carbazole SCHEMBL31681675 0.78 ALDH1A1 (0.70) ALDH1A1GPR3HSD17B10KDM4ELMNA
Carbazole SCHEMBL29105374 0.78 ALDH1A1 (0.70) ALDH1A1GPR3HSD17B10KDM4ELMNA
SCHEMBL2246482 0.75 NR4A2 (0.47) NR4A2ALDH1A1GPR3HSD17B10KDM4E
Carbazole SCHEMBL30661725 0.74 ALDH1A1 (0.64) ALDH1A1GPR3HSD17B10KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114761806-B Colorimetric detection of target materials based on hydrogel particles 高丽大学校产学协力团 2025-05-09 CN claimed
CN-114761806-A Colorimetric detection of target materials based on hydrogel particles 高丽大学校产学协力团 2022-07-15 CN claimed
CN-1469758-A Detection of the presence of a microbe or related substance at a location ����÷��̩�˹�˾ 2004-01-21 CN claimed
EP-0306772-B1 LATERAL FLOW CHROMATOGRAPHIC BINDING ASSAY DEVICE ABBOTT LABORATORIES (US) 1993-03-10 EP claimed
CN-112566940-B Multispecific WNT replacement molecules and uses thereof 瑟罗泽恩奥普瑞汀公司 2025-06-13 CN disclosed
CN-119979693-A MiRNA as biomarker for Parkinson's disease and diagnostic kit using miRNA 帕美尔生物技术有限公司 2025-05-13 CN disclosed
CN-114761806-B Colorimetric detection of target materials based on hydrogel particles 高丽大学校产学协力团 2025-05-09 CN disclosed
CN-114761579-B Method for determining whether biological sample is derived from liver cancer tissue 乐彼代株式会社 2025-04-01 CN disclosed
CN-114787386-B Method for determining whether a biological sample is derived from liver tissue 乐彼代株式会社 2025-04-01 CN disclosed
CN-111344417-B MiRNA as biomarker for Parkinson's disease and diagnostic kit using miRNA 国民大学校产学协力团 2025-01-28 CN disclosed
CN-112839710-B Determination of Parkinson's disease 霍夫曼-拉罗奇有限公司 2024-09-17 CN disclosed
CN-118516457-A MiRNA as biomarker for Parkinson's disease and diagnostic kit using miRNA 国民大学校产学协力团 2024-08-20 CN disclosed
EP-0569533-A1 ARYL MACROCYCLIC COMPOSITIONS FOR TREATING VIRAL INFECTIONS GENELABS TECHNOLOGIES, INC. (US) 1993-11-18 EP disclosed
WO-1993020445-A1 IMMUNOASSAY FOR DETECTING HCV IgM ANTIBODY ABBOTT LABORATORIES (US) 1993-10-14 WO disclosed
WO-1993016191-A1 EMPTY MAJOR HISTOCOMPATIBILITY CLASS II HETERODIMERS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1993-08-19 WO disclosed
US-5166173-A Macrocyclic chromotropic sulfur acids with polar substituents GENELABS INCORPORATED (US) 1992-11-24 US disclosed
WO-1992012709-A1 ARYL MACROCYCLIC COMPOSITIONS FOR TREATING VIRAL INFECTIONS GENELABS TECHNOLOGIES, INC. (US) 1992-08-06 WO disclosed
US-4917998-A Reaction product of body fluid with monoclonal antibody EPITOPE, INC. (US) 1990-04-17 US disclosed
US-4904581-A TESTING FOR BINDING OF MONOCLONAL ANTIBODIES, DIAGNOSTIC KITS WITH LABELING MATERIALS EPITOPE, INC. (US) 1990-02-27 US disclosed
EP-0248534-A2 Method of detecting AIDS virus infection EPITOPE, INC. (US) 1987-12-09 EP disclosed