Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.49 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335893 | 0.91 | GPR119 (0.50) | GPR119TBK1NPBWR1MCHR1 | |
| SCHEMBL1550799 | 0.80 | GPR119 (0.46) | GPR119TBK1JAK2JAK1 | |
| SCHEMBL1550797 | 0.80 | GPR119 (0.46) | GPR119TBK1JAK2JAK1 | |
| SCHEMBL2336445 | 0.79 | GPR119 (0.56) | GPR119 | |
| SCHEMBL2336693 | 0.79 | GPR119 (0.65) | GPR119JAK2JAK1 | |
| SCHEMBL2458075 | 0.78 | GPR119 (0.49) | GPR119 | |
| SCHEMBL12333878 | 0.78 | GPR119 (0.51) | GPR119NPBWR1MCHR1PDE4D | |
| SCHEMBL2520515 | 0.77 | GPR119 (0.66) | GPR119NPBWR1MCHR1 | |
| SCHEMBL8089497 | 0.76 | GPR119 (0.56) | GPR119TBK1PDE4D | |
| SCHEMBL2544987 | 0.76 | GPR119 (0.50) | GPR119TBK1NPBWR1MCHR1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011707-A2 | SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2012-01-26 | — | — | WO | disclosed |