Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 3/20 | 0.38 |
| ▸ | ATP4B | P51164 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 3/20 | 0.37 |
| ▸ | GABRD | O14764 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.37 |
| ▸ | GABRE | P78334 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601067 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4EL3MBTL1MAPTATP4A | |
| SCHEMBL4600316 | 0.90 | ALDH1A1 (0.46) | ALDH1A1KDM4EATP4AATP4BHDAC1 | |
| SCHEMBL4600310 | 0.90 | ALDH1A1 (0.46) | ALDH1A1KDM4EATP4AATP4BHDAC1 | |
| SCHEMBL4600669 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KDM4EATP4AATP4BHDAC1 | |
| SCHEMBL4600664 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KDM4EATP4AATP4BHDAC1 | |
| SCHEMBL4601572 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTATP4AATP4B | |
| SCHEMBL4601568 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTATP4AATP4B | |
| SCHEMBL4600666 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EATP4AATP4BHDAC1 | |
| SCHEMBL4600661 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EATP4AATP4BHDAC1 | |
| SCHEMBL4599488 | 0.83 | MAPT (0.35) | ALDH1A1KDM4EL3MBTL1MAPTATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718648-B1 | TRICYCLIC IMIDAZOPYRIDINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | NYCOMED GMBH (DE) | 2008-04-23 | — | — | EP | disclosed |
| EP-1718648-A1 | TRICYCLIC IMIDAZOPYRIDINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | Altana Pharma AG (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005077949-A1 | TRICYCLIC IMIDAZOPYRIDINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | ALTANA PHARMA AG (DE) | 2005-08-25 | — | — | WO | disclosed |