SCHEMBL4601196

SCHEMBL4601196

CCCCCC[C@@H](C)OC(=O)CCC

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.63
CNR1 P21554 1/20 0.63
CNR2 P34972 1/20 0.63
LMNA P02545 3/20 0.58
MAPT P10636 3/20 0.50
MAPK1 P28482 1/20 0.50
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
NAAA Q02083 1/20 0.44
EPHX2 P34913 1/20 0.44
PRKCA P17252 1/20 0.44
PRKCE Q02156 1/20 0.44
PRKCQ Q04759 1/20 0.44
PRKCD Q05655 1/20 0.44
FFAR4 Q5NUL3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9447587 1.00 FAAH (0.63) FAAHCNR1CNR2LMNAMAPT
SCHEMBL4600576 1.00 FAAH (0.63) FAAHCNR1CNR2LMNAMAPT
SCHEMBL29829684 1.00 FAAH (0.63) FAAHCNR1CNR2LMNAMAPT
SCHEMBL11787690 0.98 FAAH (0.61) FAAHCNR1CNR2LMNAMAPT
SCHEMBL8362073 0.98 FAAH (0.60) FAAHCNR1CNR2LMNAMAPT
SCHEMBL9986402 0.94 FAAH (0.65) FAAHCNR1CNR2LMNAMAPT
SCHEMBL27918401 0.94 FAAH (0.65) FAAHCNR1CNR2LMNAMAPT
SCHEMBL365376 0.92 LMNA (0.69) FAAHCNR1CNR2LMNAMAPT
SCHEMBL22223951 0.92 LMNA (0.69) FAAHCNR1CNR2LMNAMAPT
SCHEMBL9768561 0.92 LMNA (0.69) FAAHCNR1CNR2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906417-B1 CROSS-LINKED PROTEIN CRYSTAL FORMULATIONS AND THEIR USE AS CATALYSTS IN ORGANIC SOLVENTS ALTUS PHARMACEUTICALS INC (US) 2008-04-23 EP disclosed
EP-1283898-B1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS DSM IP ASSETS BV (NL) 2006-05-10 EP disclosed
US-6841691-B2 Process for the preparation of enantiomerically enriched esters and alcohols DSM N.V. (NL) 2005-01-11 US disclosed
US-20040077059-A1 Process for the preparation of enantiomerically enriched esters and alcohols DSM IP ASSETS B.V. (NL) 2004-04-22 US disclosed
EP-1283898-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS DSM N.V. (NL) 2003-02-19 EP disclosed
WO-2001090396-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS DSM N.V. (NL) 2001-11-29 WO disclosed
US-6042824-A COMBINING THE SUBSTRATE AND A CROSSLINKED ENZYME CRYSTAL FORMULATION CONTAINING A CROSSLINKED ENZYME AND A SURFACTANT WHICH ACTS UPON THE SUBSTRATE IN PRESENCE OF ORGANIC SOLVENT OR AQUEOUS-ORGANIC SOLVENT TO FORM A PRODUCT ALTUS BIOLOGICS, INC. (US) 2000-03-28 US disclosed
US-5932212-A BLEND CONTAINING SURFACTANT; BIOCATALYST ALTUS BIOLOGICS, INC. (US) 1999-08-03 US disclosed
EP-0906417-A1 CROSS-LINKED PROTEIN CRYSTAL FORMULATIONS AND THEIR USE AS CATALYSTS IN ORGANIC SOLVENTS Altus Biologics Inc. (US) 1999-04-07 EP disclosed
WO-1997044445-A1 CROSS-LINKED PROTEIN CRYSTAL FORMULATIONS AND THEIR USE AS CATALYSTS IN ORGANIC SOLVENTS ALTUS BIOLOGICS INC. (US) 1997-11-27 WO disclosed
US-5395935-A Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents PFIZER INC. (US) 1995-03-07 US disclosed
US-5270206-A Enzymatic resolution of endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents PFIZER INC. (US) 1993-12-14 US disclosed
US-5256569-A Reacting alcohols with triglycerides CHISSO CORPORATION (JP) 1993-10-26 US disclosed
EP-0231089-B1 PROCESS FOR PRODUCING AN OPTICALLY ACTIVE ALCOHOL BY A BIOCHEMICAL METHOD Chisso Corporation (JP) 1992-09-30 EP disclosed
WO-1991007501-A1 ENZYMATIC RESOLUTION OF ENDO-BICYCLO[2.2.1]HEPTAN-2-OL AND DERIVED PHARMACEUTICAL AGENTS PFIZER INC. (US) 1991-05-30 WO disclosed
EP-0231089-A2 Process for producing an optically active alcohol by a biochemical method Chisso Corporation (JP) 1987-08-05 EP disclosed