Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL2598157 | 0.82 | ALDH1A1 (0.75) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 | |
| Biphenyl SCHEMBL4466468 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 | |
| Biphenyl SCHEMBL5459788 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 | |
| Biphenyl SCHEMBL27550995 | 0.78 | ALDH1A1 (0.69) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 | |
| Biphenyl SCHEMBL27335451 | 0.78 | ALDH1A1 (0.69) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 | |
| Biphenyl SCHEMBL27709311 | 0.78 | ALDH1A1 (0.69) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 | |
| Biphenyl SCHEMBL27745920 | 0.78 | ALDH1A1 (0.69) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 | |
| Biphenyl SCHEMBL383979 | 0.78 | ALDH1A1 (0.69) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 | |
| Biphenyl SCHEMBL22288245 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 | |
| Biphenyl SCHEMBL1193167 | 0.74 | ALDH1A1 (0.53) | ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100535054-C | Silica film forming material, silica film and preparation method thereof | FUJITSU LTD (JP) | 2009-09-02 | — | — | CN | disclosed |
| EP-1727814-B1 | NUCLEOSIDE ANALOGUES WITH ANTIVIRAL ACTIVITY | UNIV CATANIA (IT) | 2008-04-30 | — | — | EP | disclosed |
| CN-1891757-A | Silica film forming material, silica film and method of manufacturing the same | FUJITSU LTD (JP) | 2007-01-10 | — | — | CN | disclosed |
| EP-1727814-A1 | NUCLEOSIDE ANALOGUES WITH ANTIVIRAL ACTIVITY | Universita' Degli Studi Di Catania (IT) | 2006-12-06 | — | — | EP | disclosed |
| EP-1546164-A4 | (+)-TRANS-ISOMERS OF (1-PHOSPHONOMETHOXY-2-ALKYLCYCLOPROPYL) METHYL NUCLEOSIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF STEREOISOMERS THEREOF, AND USE OF ANTIVIRAL AGENTS THEREOF | LG LIFE SCIENCES LTD (KR) | 2006-06-07 | — | — | EP | disclosed |
| US-20060111324-A1 | (+)-Ttrans-isomers of (1-phosphonomethoxy-2-alkylcyclopropyl)methyl nucleoside derivatives, process for the preparation of stereoisomers thereof, and use of antiviral agents thereof | LG LIFE SCIENCES (KR) | 2006-05-25 | — | — | US | disclosed |
| WO-2005082896-A1 | NUCLEOSIDE ANALOGUES WITH ANTIVIRAL ACTIVITY | UNIVERSITA' DEGLI STUDI DI CATANIA (IT) | 2005-09-09 | — | — | WO | disclosed |
| EP-1546164-A1 | (+)-TRANS-ISOMERS OF (1-PHOSPHONOMETHOXY-2-ALKYLCYCLOPROPYL) METHYL NUCLEOSIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF STEREOISOMERS THEREOF, AND USE OF ANTIVIRAL AGENTS THEREOF | LG Life Sciences Ltd. (KR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004029064-A1 | (+)-TRANS-ISOMERS OF (1-PHOSPHONOMETHOXY-2-ALKYLCYCLOPROPYL) METHYL NUCLEOSIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF STEREOISOMERS THEREOF, AND USE OF ANTIVIRAL AGENTS THEREOF | LG LIFE SCIENCES LTD. (KR) | 2004-04-08 | — | — | WO | disclosed |
| US-5401649-A | Conjugated with luminescent label, immunogenic carrier, ligand, enzyme, or hapten, detection of cyclosporins | SYNTEX (U.S.A.) INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-5300634-A | Process for producing maltooligosaccharide derivative | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0512808-A1 | Process for producing maltooligosaccharide derivative | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-5089390-A | Determination of cyclosporins with luninescent labeled conjugate; immunoassay | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111324-A1 | (+)-Ttrans-isomers of (1-phosphonomethoxy-2-alkylcyclopropyl)methyl nucleoside derivatives, process for the preparation of stereoisomers thereof, and use of antiviral agents thereof | TTR, HAVCR2, PNP | ALDH1A1 1984/4885CYP1A2 1326/4885SLC22A2 1740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.