Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CMA1 | P23946 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | LPO | P22079 | 3/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459616 | 0.87 | MAPT (0.48) | MAPTTP53LMNACMA1CHRM5 | |
| SCHEMBL459562 | 0.80 | POLB (0.47) | MAPTLMNAP2RX7 | |
| SCHEMBL461145 | 0.77 | MAPT (0.59) | MAPTTP53LMNACMA1LPO | |
| SCHEMBL459682 | 0.74 | MAPT (0.45) | MAPTLMNA | |
| SCHEMBL5197596 | 0.74 | TP53 (0.52) | MAPTTP53LMNACMA1ADRA1D | |
| SCHEMBL5435624 | 0.74 | MAPT (0.61) | MAPTTP53LMNACMA1LPO | |
| SCHEMBL5184783 | 0.73 | MAPT (0.54) | MAPTTP53LMNACMA1ADRA1D | |
| SCHEMBL23168654 | 0.73 | MAPT (0.51) | MAPTTP53LMNACMA1ADRA1D | |
| SCHEMBL29821419 | 0.73 | MAPT (0.51) | MAPTTP53LMNACMA1ADRA1D | |
| SCHEMBL10080764 | 0.73 | MAPT (0.44) | MAPTLMNAP2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011707-A2 | SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2012-01-26 | — | — | WO | disclosed |