Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460897 | 0.85 | ALDH1A1 (0.48) | THRBEGLN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10080764 | 0.82 | MAPT (0.44) | POLBTHRBEGLN1LMNASMN1; SMN2 | |
| SCHEMBL460146 | 0.80 | MAPT (0.55) | LMNAP2RX7MAPT | |
| SCHEMBL10080865 | 0.80 | L3MBTL1 (0.56) | BRD4EGLN1HSD17B13P2RX7 | |
| SCHEMBL4378877 | 0.75 | MAPK14 (0.49) | POLBTHRBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL459682 | 0.74 | MAPT (0.45) | POLBTHRBEGLN1LMNASMN1; SMN2 | |
| SCHEMBL1770022 | 0.74 | POLB (0.44) | POLBTHRBBRD4MKNK1MKNK2 | |
| SCHEMBL3524356 | 0.73 | HSD17B13 (0.47) | POLBTHRBBRD4MKNK1MKNK2 | |
| SCHEMBL459616 | 0.73 | MAPT (0.48) | LMNAALDH1A1HSP90AA1MAPT | |
| SCHEMBL1770079 | 0.73 | POLB (0.48) | POLBTHRBBRD4MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011707-A2 | SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2012-01-26 | — | — | WO | disclosed |