Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460146 | 0.87 | MAPT (0.55) | MAPTTP53CMA1LMNAKMT2A | |
| SCHEMBL459682 | 0.81 | MAPT (0.45) | MAPTLMNAALDH1A1NPBWR1 | |
| SCHEMBL460897 | 0.81 | ALDH1A1 (0.48) | MAPTTP53LMNAMEN1ALDH1A1 | |
| SCHEMBL10080764 | 0.77 | MAPT (0.44) | MAPTLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL9670234 | 0.75 | BAZ2B (0.33) | LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL2458827 | 0.75 | CMA1 (0.51) | MAPTTP53CMA1LMNAALDH1A1 | |
| SCHEMBL4295434 | 0.75 | MAPT (0.62) | MAPTTP53CMA1LMNAGSK3A | |
| SCHEMBL26121258 | 0.74 | MAPT (0.48) | MAPTTP53CMA1LMNAMEN1 | |
| SCHEMBL28500694 | 0.73 | CHRM1 (0.50) | MAPTTP53CMA1LMNAMEN1 | |
| SCHEMBL18300546 | 0.73 | IDO1 (0.48) | MAPTTP53CMA1LMNAGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011707-A2 | SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2012-01-26 | — | — | WO | disclosed |