Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693830 | 0.94 | THRB (0.58) | THRBLMNAALDH1A1PTPN1ACACB | |
| SCHEMBL30340 | 0.94 | — | — | |
| SCHEMBL3729744 | 0.94 | — | — | |
| SCHEMBL721854 | 0.94 | — | — | |
| Glycerin SCHEMBL28966317 | 0.91 | THRB (0.61) | THRBLMNAALDH1A1PTPN1USP2 | |
| Water SCHEMBL3354792 | 0.91 | — | — | |
| SCHEMBL3844086 | 0.91 | THRB (0.42) | THRBLMNAALDH1A1PTPN1ACACB | |
| SCHEMBL26110715 | 0.91 | THRB (0.42) | THRBLMNAALDH1A1PTPN1ACACB | |
| SCHEMBL1746817 | 0.89 | THRB (0.52) | THRBLMNAALDH1A1PTPN1ACACB | |
| SCHEMBL8952135 | 0.88 | THRB (0.77) | THRBLMNAALDH1A1PTPN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906417-B1 | CROSS-LINKED PROTEIN CRYSTAL FORMULATIONS AND THEIR USE AS CATALYSTS IN ORGANIC SOLVENTS | ALTUS PHARMACEUTICALS INC (US) | 2008-04-23 | — | — | EP | claimed |