Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603068 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1HTTLMNADPP4 | |
| SCHEMBL4602273 | 0.81 | ALDH1A1 (0.53) | KDM4EALDH1A1HTTLMNAKMT2A | |
| SCHEMBL22163870 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL21245769 | 0.80 | CPS1 (0.52) | KDM4EALDH1A1HTTLMNA | |
| SCHEMBL30198967 | 0.80 | CPS1 (0.52) | KDM4EALDH1A1HTTLMNA | |
| SCHEMBL22172219 | 0.79 | CPS1 (0.48) | KDM4EALDH1A1HTTLMNA | |
| SCHEMBL4602793 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HTT | |
| SCHEMBL22172226 | 0.78 | GPR183 (0.49) | KDM4EALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL22172181 | 0.78 | PIK3CA (0.49) | KDM4EALDH1A1HTTLMNAKMT2A | |
| SCHEMBL30309550 | 0.78 | GPR183 (0.49) | KDM4EALDH1A1HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761520-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2008-07-09 | — | — | EP | disclosed |