Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516564 | 0.85 | TDP1 (0.82) | TDP1KDM4ELMNAALDH1A1ALOX5 | |
| SCHEMBL26698258 | 0.83 | TSHR (0.50) | TDP1KDM4ELMNAALDH1A1ALOX5 | |
| SCHEMBL27839288 | 0.81 | TDP1 (0.63) | TDP1KDM4ELMNAALDH1A1ALOX5 | |
| SCHEMBL13335015 | 0.81 | TDP1 (0.74) | TDP1KDM4ELMNAALDH1A1ALOX5 | |
| SCHEMBL29086538 | 0.80 | TDP1 (0.73) | TDP1ALDH1A1KEAP1KMT2ARAB9A | |
| SCHEMBL28638406 | 0.80 | TDP1 (0.54) | TDP1LMNAALDH1A1TSHRFFAR1 | |
| SCHEMBL8494006 | 0.80 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AMAPT | |
| Methyl 3-Phenylpropanoate SCHEMBL168711 | 0.77 | TDP1 (0.68) | TDP1KDM4ELMNAALDH1A1KEAP1 | |
| SCHEMBL12301101 | 0.76 | TDP1 (0.72) | TDP1KDM4ELMNAALDH1A1ALOX5 | |
| SCHEMBL24241943 | 0.76 | ALOX5 (0.59) | TDP1KDM4ELMNAALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |