Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601952 | 0.83 | TDP1 (0.59) | TSHRALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL9736831 | 0.82 | ALDH1A1 (0.61) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL9065264 | 0.81 | TSHR (0.49) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| Ammonia Solution, Strong SCHEMBL27732594 | 0.81 | ALDH1A1 (0.59) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL18554127 | 0.80 | MEN1 (0.48) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL28392150 | 0.80 | MAPK1 (0.46) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL4966165 | 0.80 | TSHR (0.58) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL28008659 | 0.79 | LMNA (0.53) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL664857 | 0.79 | ALDH1A1 (0.65) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| Benzene SCHEMBL9407299 | 0.79 | ALDH1A1 (0.65) | TSHRALDH1A1L3MBTL1MAPK1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |