Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508202 | 0.93 | CES1 (0.56) | CES1KCNN4CES2TSHRDAO | |
| SCHEMBL15519395 | 0.93 | CES1 (0.56) | CES1KCNN4CES2TSHRDAO | |
| SCHEMBL30610236 | 0.79 | CES1 (0.55) | CES1KCNN4CES2ALDH1A1CYP1A2 | |
| SCHEMBL11661275 | 0.78 | CES1 (0.50) | CES1TSHRDAONAPRTALDH1A1 | |
| SCHEMBL17080312 | 0.77 | CES1 (0.58) | CES1KCNN4CES2ALDH1A1L3MBTL1 | |
| SCHEMBL1666976 | 0.75 | CES1 (0.61) | CES1KCNN4CES2TSHRDAO | |
| SCHEMBL6248474 | 0.73 | CES1 (0.54) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL1079930 | 0.73 | CES1 (0.54) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL242506 | 0.73 | CES1 (0.54) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL562162 | 0.73 | CES1 (0.54) | CES1CES2TSHRDAONAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905184-B1 | Aromatic polycarbonate resin composition | GEN ELECTRIC (US) | 2008-04-23 | — | — | EP | disclosed |
| US-5973101-A | COMPRISING A STABILIZER DEACTIVATING THE METAL IMPURITY, PREVENTING THE INTERACTION OF HYDROXYL END GROUPS OF POLYCARBONATES WITH METALS | GENERAL ELECTRIC COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0905184-A2 | Aromatic polycarbonate resin composition | GENERAL ELECTRIC COMPANY (US) | 1999-03-31 | — | — | EP | disclosed |