Dioxane

Dioxane

SCHEMBL460231

C1CCOC1.C1COCCO1

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.89
TTR P02766 1/20 0.67
TSHR P16473 1/20 0.50
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31
LMNA P02545 2/20 0.30
CRHBP P24387 2/20 0.30
HTT P42858 2/20 0.30
CRHR2 Q13324 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL9498119 1.00 ALDH1A1 (0.89) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL3221558 1.00 ALDH1A1 (0.89) ALDH1A1TTRTSHRMEN1KMT2A
Dioxane SCHEMBL28105552 1.00 ALDH1A1 (0.89) ALDH1A1TTRTSHRMEN1KMT2A
Tetrahydrofuran SCHEMBL10829410 1.00 ALDH1A1 (0.89) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL3391604 1.00 ALDH1A1 (0.89) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL541039 1.00
Tetrahydrofuran SCHEMBL112157 1.00
Tetrahydrofuran SCHEMBL317459 1.00 ALDH1A1 (0.89) ALDH1A1TTRTSHRMEN1KMT2A
Tetrahydrofuran SCHEMBL7999698 1.00 ALDH1A1 (0.89) ALDH1A1TTRTSHRMEN1KMT2A
Oxirane SCHEMBL9421789 0.95 ALDH1A1 (0.80) ALDH1A1TTRTSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4188585-B1 METHOD OF PRODUCING CARBON MOLECULAR SIEVE MEMBRANES DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-19 EP claimed
WO-2024127418-A1 INJECTABLE COMPOSITIONS OF POSACONAZOLE CIPLA LIMITED (IN) 2024-06-20 WO claimed
CN-118048677-A Perovskite single crystal growth system and method based on pressure and temperature combination control 山东大学 2024-05-17 CN claimed
CN-117865773-A Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling 大连理工大学 2024-04-12 CN claimed
CN-117488423-A Preparation method and application of passive cooling photo-thermal regulation fiber and fabric 武汉格物感知信息科技有限公司 2024-02-02 CN claimed
US-20230278006-A1 METHOD OF PRODUCING CARBON MOLECULAR SIEVE MEMBRANES DOW GLOBAL TECHNOLOGIES LLC (US) 2023-09-07 US claimed
EP-4188585-A1 METHOD OF PRODUCING CARBON MOLECULAR SIEVE MEMBRANES Dow Global Technologies LLC (US) 2023-06-07 EP claimed
CN-110272462-B Process for preparing compounds 南开大学 2023-03-10 CN claimed
CN-115010563-A Method for preparing different halogenated aromatic hydrocarbons by visible light promoted nickel-catalyzed halogen exchange 大连理工大学 2022-09-06 CN claimed
CN-112480107-B Substituted azabicyclooctane compounds, intermediates therefor and processes for their preparation 上海海雁医药科技有限公司 2022-08-16 CN claimed
US-5292902-A Process for the manufacture of odorants and intermediates used therein GIVAUDAN-ROURE CORPORATION (US) 1994-03-08 US claimed
US-5140087-A Endcapped by a polyfluoroalkylsilanol at one end and a silanol at the other; molecular weight distribution; silicone rubbers; oil repellants CHISSO CORPORATION (JP) 1992-08-18 US claimed
EP-0376012-A2 Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1990-07-04 EP claimed
EP-0274353-B1 PROCESS FOR THE PREPARATION OF BENZOIN SULFONATES CIBA-GEIGY AG (CH) 1990-02-07 EP claimed
EP-0157284-B1 THEOPHYLLINE-7-ACETIC ACID ESTER OF D,L-TRANS-SOBREROL HAVING MUCOSECRETOLYTIC-FLUIDIZING AND ANTIBRONCHOSPASTIC ACTIVITY, A PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF CAMILLO CORVI S.p.A. (IT) 1989-08-09 EP claimed
EP-0166918-B1 A (-) CAMPHOLENIC ACID ESTER OF SALICYLIC ACID HAVING MUCOSECRETOLYTIC, ANTI-INFLAMMATORY, ANALGESIC ANTIPYRETIC ACTIVITY, SUITABLE TO PROVIDE PHARMACEUTICALLY ACCEPTABLE SALTS; A PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE ESTER OR THE SALTS THEREOF CAMILLO CORVI S.p.A. (IT) 1989-07-12 EP claimed
EP-0166135-B1 AN ESTER OF (+)6-METHOXY- ALPHA -METHYL-2-NAPHTALENE ACETIC ACID HAVING MUCOSECRETOLYTIC, ANTI-INFLAMMATORY, ANALGESIC, ANTIPYRETIC ACTIVITY, A PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF CAMILLO CORVI S.p.A. (IT) 1989-06-14 EP claimed
US-4808743-A Vinyl chloroformates and preparation SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1989-02-28 US claimed
EP-0204481-A2 Process for optically active threo-3-(3,4-methylenedioxyphenyl) serine SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1986-12-10 EP claimed
US-4310704-A Process for manufacturing methyl ketones by oxidation of terminal olefins INSTITUT FRANCAIS DU PETROLE (FR) 1982-01-12 US claimed