SCHEMBL296248

SCHEMBL296248

C=Cc1ccccc1CCO[SiH3]

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MITF O75030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2404989 0.84 ALDH1A1 (0.40) ALDH1A1HPGDHTTSMN1; SMN2MITF
SCHEMBL29377653 0.81 ALDH1A1 (0.48) ALDH1A1MITF
SCHEMBL595200 0.81 ALDH1A1 (0.48) ALDH1A1MITF
SCHEMBL4602387 0.81 ALDH1A1 (0.38) ALDH1A1HPGDHTTSMN1; SMN2MITF
SCHEMBL4929094 0.80 ALDH1A1 (0.40) ALDH1A1
SCHEMBL29066993 0.79 CA1 (0.38) ALDH1A1HPGDSMN1; SMN2
SCHEMBL5072509 0.79 ALDH1A1 (0.46) ALDH1A1MITF
SCHEMBL9772095 0.78 ALDH1A1 (0.41) ALDH1A1MITF
SCHEMBL31054112 0.77 ALDH1A1 (0.44) ALDH1A1MITF
SCHEMBL6278153 0.77 ALDH1A1 (0.44) ALDH1A1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12331164-B2 Curable siloxane resin composition KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-06-17 US claimed
CN-116082843-A Heat-resistant addition type silicone rubber composition and preparation method thereof 东莞市贝特利新材料有限公司 2023-05-09 CN claimed
CN-116023407-A Modified alkoxy silane and preparation method thereof, dealcoholized silicone weather-resistant sealant prepared from modified alkoxy silane and preparation method thereof 广州市白云化工实业有限公司 2023-04-28 CN claimed
US-20230078587-A1 CURABLE SILOXANE RESIN COMPOSITION KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-03-16 US claimed
CN-111978481-A Alkali-free water reducing agent and preparation method thereof 东莞创利科技发展有限公司 2020-11-24 CN claimed
EP-2470574-B1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORP (JP) 2014-09-17 EP claimed
US-8765887-B2 Process and catalyst system for polydiene production BRIDGESTONE CORPORATION (JP) 2014-07-01 US claimed
EP-2470574-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION Bridgestone Corporation (JP) 2012-07-04 EP claimed
US-20120165484-A1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2012-06-28 US claimed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP claimed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US claimed
WO-2011028523-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2011-03-10 WO claimed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP claimed
JP-2008523165-A 2008-07-03 JP claimed
EP-1833880-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS Matsushita Electric Works, Ltd. (JP) 2007-09-19 EP claimed
EP-1769512-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS Dow Corning Corporation (US) 2007-04-04 EP claimed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
WO-2005124792-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS DOW CORNING CORPORATION (US) 2005-12-29 WO claimed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-12434265-B2 Coating method TOKUYAMA CORPORATION (JP) 2025-10-07 US disclosed
US-12331164-B2 Curable siloxane resin composition KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-06-17 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
CN-115702176-B Curable composition and cured product thereof 株式会社德山 2024-05-03 CN disclosed
US-11767388-B1 Silicon-functionalized rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2023-09-26 US disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 US disclosed
CN-116082843-A Heat-resistant addition type silicone rubber composition and preparation method thereof 东莞市贝特利新材料有限公司 2023-05-09 CN disclosed
US-20230078587-A1 CURABLE SILOXANE RESIN COMPOSITION KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-03-16 US disclosed
CN-115702176-A Curable composition and cured product thereof 株式会社德山 2023-02-14 CN disclosed
US-11542621-B1 Coatings and coated surfaces including low-surface energy inorganic particles MAXTERIAL, INC. (US) 2023-01-03 US disclosed
US-20220234072-A1 COATING METHOD TOKUYAMA CORPORATION (JP) 2022-07-28 US disclosed
EP-4000750-A1 COATING METHOD Tokuyama Corporation (JP) 2022-05-25 EP disclosed
CN-114126768-A Coating method 株式会社德山 2022-03-01 CN disclosed
WO-2021015138-A1 COATING METHOD 株式会社トクヤマ 2021-01-28 WO disclosed
CN-111978481-A Alkali-free water reducing agent and preparation method thereof 东莞创利科技发展有限公司 2020-11-24 CN disclosed
EP-3691894-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM Maxterial, Inc. (US) 2020-08-12 EP disclosed
CN-111405980-A Article comprising a surface coating and method for producing the same 麦克斯特里尔有限公司 2020-07-10 CN disclosed
CN-107109130-B Polysiloxanes as anti-adhesion and anti-fouling additives, method for their production and use 毕克化学有限公司 2019-12-31 CN disclosed
US-20190186035-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2019-06-20 US disclosed
WO-2019067950-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL, INC. (US) 2019-04-04 WO disclosed
EP-3397788-A1 COATINGS AND COATED SURFACES WITH SELECTED SURFACE CHARACTERISTICS AND FEATURES Maxterial, Inc. (US) 2018-11-07 EP disclosed
US-9994676-B2 Silicon-containing polymer and method of making a silicon-containing polymer 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-06-12 US disclosed
US-9977161-B2 Curable composition, cured article obtained therefrom, and photochromic optical material and process for producing the same TOKUYAMA CORPORATION (JP) 2018-05-22 US disclosed
US-9938432-B2 Polysiloxanes as anti-adhesive and dirt-repellant additives, method for the production and use thereof BYK Chemie, GmbH (DE) 2018-04-10 US disclosed
US-20180028029-A1 DRYING APPARATUS COMPRISING A HYDROPHOBIC MATERIAL HAGHDOOST ATIEH (US) 2018-02-01 US disclosed
US-20170334170-A1 ARTICLES INCLUDING ADHESION ENHANCING COATINGS AND METHODS OF PRODUCING THEM HAGHDOOST ATIEH (US) 2017-11-23 US disclosed
US-20170247572-A1 POLYSILOXANES AS ANTI-ADHESIVE AND DIRT-REPELLANT ADDITIVES, METHOD FOR THE PRODUCTION AND USE THEREOF BYK-CHEMIE GMBH (DE) 2017-08-31 US disclosed
US-20170190139-A1 COATINGS AND COATED SURFACES WITH SELECTED SURFACE CHARACTERISTICS AND FEATURES HAGHDOOST ATIEH (US) 2017-07-06 US disclosed
US-20170183448-A1 SILICON-CONTAINING POLYMER AND METHOD OF MAKING A SILICON-CONTAINING POLYMER 3M INNOVATIVE PROPERTIES COMPANY 2017-06-29 US disclosed
WO-2015200003-A1 SILICON-CONTAINING POLYMER AND METHOD OF MAKING A SILICON-CONTAINING POLYMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-12-30 WO disclosed
US-8946369-B2 Branched polysiloxanes and use of these EVONIK DEGUSSA GMBH (DE) 2015-02-03 US disclosed
EP-1535980-B1 PHOTOCHROMIC COMPOSITION TOKUYAMA CORP (JP) 2014-10-29 EP disclosed
EP-2470574-B1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORP (JP) 2014-09-17 EP disclosed
US-8765887-B2 Process and catalyst system for polydiene production BRIDGESTONE CORPORATION (JP) 2014-07-01 US disclosed
US-8643200-B2 Resin composition and transparent encapsulant formed using the same, and electronic device including the encapsulant Cheil Indistries, Inc. (KR) 2014-02-04 US disclosed
US-8637627-B2 Phenoxyphenyl polysiloxane composition and method for making and using same ROHM AND HAAS COMPANY (US) 2014-01-28 US disclosed
US-20130217907-A1 BRANCHED POLYSILOXANES AND USE OF THESE EVONIK GOLDSCHMIDT GMBH (DE) 2013-08-22 US disclosed
US-8409670-B2 Process for producing photochromic layered product TOKUYAMA CORPORATION (JP) 2013-04-02 US disclosed
EP-2138525-B1 EPOXY SILICONE AND METHOD FOR PRODUCTION THEREOF, AND CURABLE RESIN COMPOSITION USING THE SAME AND USE THEREOF ASAHI KASEI CHEMICALS CORP (JP) 2012-12-26 EP disclosed
US-8222348-B2 Epoxy silicone and process for producing same, and curable mix composition using same and use thereof ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-07-17 US disclosed
EP-2470574-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION Bridgestone Corporation (JP) 2012-07-04 EP disclosed
US-20120165484-A1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2012-06-28 US disclosed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP disclosed
EP-1833880-B1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC CORP (JP) 2012-03-14 EP disclosed
US-20110278640-A1 RESIN COMPOSITION AND TRANSPARENT ENCAPSULANT FORMED USING THE SAME, AND ELECTRONIC DEVICE INCLUDING THE ENCAPSULANT CHEIL INDUSTRIES, INC. (KR) 2011-11-17 US disclosed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US disclosed
US-7915369-B2 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2011-03-29 US disclosed
WO-2011028523-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2011-03-10 WO disclosed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP disclosed
US-7794782-B2 Phosphonate and sulfido silane anti-corrosion additive for electrical cable restoration fluid DOW CORNING CORPORATION (US) 2010-09-14 US disclosed
US-7763693-B2 Curable composition TOKUYAMA CORPORATION (JP) 2010-07-27 US disclosed
US-7732553-B2 Method of producing encapsulation resins THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-06-08 US disclosed
US-20100120975-A1 EPOXY SILICONE AND PROCESS FOR PRODUCING SAME, AND CURABLE MIX COMPOSITION USING SAME AND USE THEREOF ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-05-13 US disclosed
EP-1918335-B1 Coating composition and optical articles TOKUYAMA CORP (JP) 2010-04-14 EP disclosed
EP-2138525-A1 EPOXY SILICONE AND METHOD FOR PRODUCTION THEREOF, AND CURABLE RESIN COMPOSITION USING THE SAME AND USE THEREOF Asahi Kasei Chemicals Corporation (JP) 2009-12-30 EP disclosed
US-20090218592-A1 Method of producing encapsulation resins MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-03 US disclosed
EP-1568739-B1 COATING COMPOSITION AND OPTICAL ARTICLE TOKUYAMA CORP (JP) 2009-08-26 EP disclosed
US-20090146324-A1 Phenoxyphenyl polysiloxane composition and method for making and using same ROHM AND HAAS COMPANY (US) 2009-06-11 US disclosed
EP-1561571-B1 PROCESS FOR PRODUCING PHOTOCHROMIC LAYERED PRODUCT TOKUYAMA CORP (JP) 2009-05-06 EP disclosed
EP-1655342-B1 CURABLE COMPOSITION TOKUYAMA CORP (JP) 2009-01-07 EP disclosed
US-7442734-B2 Coating composition and optical article TOKUYAMA CORPORATION (JP) 2008-10-28 US disclosed
EP-1918335-A1 Coating composition and optical articles Tokuyama Corporation (JP) 2008-05-07 EP disclosed
EP-1433814-B1 CURABLE COMPOSITION, CURED ARTICLE OBTAINED THEREFROM, AND PHOTOCHROMIC OPTICAL MATERIAL AND PROCESS FOR PRODUCING THE SAME TOKUYAMA CORP (JP) 2007-12-19 EP disclosed
US-20070235700-A1 Phosphonate and Sulfido Silane Anti-Corrosion Additve for Electrical Cable Restoration Fluid DOW CORNING CORPORATION 2007-10-11 US disclosed
EP-1833880-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS Matsushita Electric Works, Ltd. (JP) 2007-09-19 EP disclosed
EP-1769512-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS Dow Corning Corporation (US) 2007-04-04 EP disclosed
US-20070065633-A1 Process for producing photochromic layered product TOKUYAMA CORPORATION (JP) 2007-03-22 US disclosed
US-7169941-B2 Photochromic composition TOKUYAMA CORPORATION (JP) 2007-01-30 US disclosed
US-20060264593-A1 Curable composition TOKUYAMA CORPORATION (JP) 2006-11-23 US disclosed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO disclosed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US disclosed
EP-1655342-A1 CURABLE COMPOSITION Tokuyama Corporation (JP) 2006-05-10 EP disclosed
US-20060071203-A1 Coating composition and optical article TOKUYAMA CORPORATION (JP) 2006-04-06 US disclosed
WO-2005124792-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS DOW CORNING CORPORATION (US) 2005-12-29 WO disclosed
EP-1568739-A1 COATING COMPOSITION AND OPTICAL ARTICLE Tokuyama Corporation (JP) 2005-08-31 EP disclosed
EP-1561571-A1 PROCESS FOR PRODUCING PHOTOCHROMIC LAYERED PRODUCT TOKUYAMA CORPORATION (JP) 2005-08-10 EP disclosed
EP-1535980-A1 PHOTOCHROMIC COMPOSITION Tokuyama Corporation (JP) 2005-06-01 EP disclosed
US-20040220292-A1 Curable composition, cured article obtained therefrom, and photochromic optical material and process for producing the same TOKUYAMA CORPORATION (JP) 2004-11-04 US disclosed
US-20040173782-A1 Photochromic composition TOKUYAMA CORPORATION (JP) 2004-09-09 US disclosed
EP-1433814-A1 CURABLE COMPOSITION, CURED ARTICLE OBTAINED THEREFROM, AND PHOTOCHROMIC OPTICAL MATERIAL AND PROCESS FOR PRODUCING THE SAME Tokuyama Corporation (JP) 2004-06-30 EP disclosed
EP-1323779-A1 Foamed polyolefin sheets with improved property spectrum Borealis GmbH (AT) 2003-07-02 EP disclosed
US-6136926-A CURING WITH ETHYLENICALLY UNSATURATED ORGANOSILANE COMPOUND; HEATING BELOW SOFTENING POINT BOREALIS GMBH (AT) 2000-10-24 US disclosed
US-5929127-A Fine-celled polyolefin foam materials BOREALIS AG (AT) 1999-07-27 US disclosed
US-5929127-A Fine-celled polyolefin foam materials BOREALIS AG (AT) 1999-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040173782-A1 Photochromic composition CRY1, CRYAA, RB1 ALDH1A1 3073/4885HPGD 3385/4885HTT 542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.