SCHEMBL4602403

SCHEMBL4602403

CCO[SiH](OCC)C(Cl)CC1CC2C=CC1C2

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603855 0.84 KDM4E (0.37) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL14761128 0.83 KDM4E (0.40) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL7531435 0.73 KDM4E (0.43) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL3277483 0.72 KDM4E (0.44) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL4661360 0.71 KDM4E (0.40) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL465320 0.70 KDM4E (0.47) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL1760600 0.70 KDM4E (0.41) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL4602396 0.70
SCHEMBL14761127 0.69 KDM4E (0.31) KDM4EALDH1A1
SCHEMBL19689430 0.68 KDM4E (0.44) KDM4EALDH1A1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20070225461-A1 Olefin polymers for imaging members LEXMARK INTERNATIONAL INC. 2007-09-27 US disclosed
US-6911507-B2 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2005-06-28 US disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed